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Št. zadetkov: 2
Supramolecular diversity of oxabicyclo[2.2.2]octenes formed between substituted 2H-pyran-2-ones and vinyl-moiety-containing dienophiles
Krištof Kranjc, Amadej Juranovič, Marijan Kočevar, Franc Perdih
Izvirni znanstveni članek
Oznake: Diels-Alderjeva reakcija;organska sinteza;heterocikli;vodikova vez;kristalna struktura;Diels-Alder reaction;organic synthesis;heterocycles;hydrogen bonds;crystal structure;
In Diels–Alder reactions, 2H-pyran-2-ones as dienes can yield a large variety of cycloadducts with up to four contiguous carbon stereogenic centers. Some of the potentially most useful, however difficult to prepare due to their low thermal stability, are the primary CO$_2$-containing oxabicyclo[2.2. ...
Leto: 2020 Vir: Fakulteta za kemijo in kemijsko tehnologijo (UL FKKT)
N-Substituted 2-isonicotinoylhydrazinecarboxamides - new antimycobacterial active molecules
Zuzana Rychtarčíková, Martin Krátký, Martin Gazvoda, Markéta Komlóová, Slovenko Polanc, Marijan Kočevar, Jiřína Stolařiková, Jarmila Vinšová
Izvirni znanstveni članek
Oznake: medicina;organska kemija;farmakologija;tuberkuloza;zdravila za zdravljenje tuberkuloze;protibakterijska aktivnost;heterociklične spojine;derivati karboksamida;derivati hidrazina;INH;InhA inhibition;in silico docking;in vitro antimycobacterial activity;2-isonicotinoylhydrazinecarboxamide;5-(pyridine-4-yl)-1,3,4-oxadiazol-2-amine;tuberculosis;
This report presents a new modification of the isoniazid (INH) structure linked with different anilines via a carbonyl group obtained by two synthetic procedures and with N-substituted 5-(pyridine-4-yl)-1,3,4-oxadiazole-2-amines prepared by their cyclisation. All synthesised derivatives were charact ...
Leto: 2014 Vir: Fakulteta za kemijo in kemijsko tehnologijo (UL FKKT)
Št. zadetkov: 2
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