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Št. zadetkov: 9
Heterogeneous response of airway eosinophilia to anti-IL-5 biologics in severe asthma patients
Maruša Kopač, Matija Rijavec, Peter Korošec, Urška Bidovec, Izidor Kern, Romana Vantur, Sabina Škrgat-Kristan, Sabina Škrgat-Kristan
Izvirni znanstveni članek
Oznake: težka astma;anti-IL-5 biološka zdravila;eozinofilija;dihalne poti;sputum;
Many questions concerning responders (R) and nonresponders (NR) in severe eosinophilic asthma (SEA) after blocking the IL-5 (interleukin 5) pathway are still not clear, especially regarding the early parameters of response to biologics in personalized treatment strategies. We evaluated 17 SEA patien ...
Leto: 2022 Vir: Digitalni repozitorij raziskovalnih organizacij Slovenije
Pljučni rak in kajenje
Janez Eržen, Sabina Škrgat-Kristan
Objavljeni znanstveni prispevek na konferenci
Oznake:
Pljučni rak in kajenje
Leto: 1998 Vir: Onkološki inštitut Ljubljana (OI)
Kako dolgo imajo bolniki z erythema migrans prisesane klope
Andreja Funa, Tina Šavs, Sabina Škrgat-Kristan
Izvirni znanstveni članek
Oznake: klopi;Lyme borelioza;medicina;okužbe
Experiments on animals have demonstrated that during the initial 24 hours of tic attachment, the likelihood of transmission of Borrelia burgdorferi, the causative agent of Lyme disease, from an infected tick to the host is negligible. The risk of infection increases abruptly with attachment times 48 ...
Leto: 1996 Vir: dLib.si Digitalna knjižnica Slovenije
Kako izbrati in tolmačiti rezultate preiskave pljučne funkcije pri astmi in KOPB
Matjaž Fležar, Stanislav Šuškovič, Sabina Škrgat-Kristan, Mitja Košnik
Pregledni znanstveni članek
Oznake:
Background: Lung function testing consists of different tests to determine obstructive or restrictive lung disease. It includes tests for lung mechanics - measurements of lung volumes and flows, tests for gas exchange (diffusion capacity of the lung, blood gas analysis) and tests that confirm airway ...
Leto: 2011 Vir: dLib.si Digitalna knjižnica Slovenije
Ocena kakovosti življenja bolnika s kronično obstruktivno pljučno boleznijo: vprašalnik St. George v povezavi s funkcijskimi testi
Marjana Bratkovič, Jurij Šorli, Miljana Vegnuti, Sabina Škrgat-Kristan
Izvirni znanstveni članek
Oznake:
Introduction: Chronic obstructive pulmonary disease (COPD) has a detrimental effect on the performance of daily activities and consequently on health-relaCed quality of life (HRQOL). Different HRQOL instruments have been developed to quantify the impact of COPD on a patient's daily life, and are use ...
Leto: 2009 Vir: dLib.si Digitalna knjižnica Slovenije
T2-high asthma, classified by sputum mRNA expression of IL4, IL5, and IL13, is characterized by eosinophilia and severe phenotype
Matija Rijavec, Tomaž Krumpestar, Sabina Škrgat-Kristan, Izidor Kern, Peter Korošec
Izvirni znanstveni članek
Oznake: težka astma;endotip;IL-4;IL-5;IL-13;biološko zdravljenje;severe asthma;endotype;biologic treatment;
Asthma is a common chronic disease, with different underlying inflammatory mechanisms. Identification of asthma endotypes, which reflect a variable response to different treatments, is important for more precise asthma management. T2 asthma is characterized by airway inflammation driven by T2 cytoki ...
Leto: 2021 Vir: Digitalni repozitorij raziskovalnih organizacij Slovenije
Sodobno vodenje trajne astme
Mitja Košnik, Stanislav Šuškovič, Matjaž Fležar, Katarina Osolnik, Mihaela Zidarn, Sabina Škrgat-Kristan, Saša Kadivec
Strokovni članek
Oznake:
Asthma afflicts at least 5% of the population. The patients have difficulties in breathing because air ways are narrowed due to the inflammation process. Measures which abate asthma inflammation help to control the disease. The inflammation is coped with by elimination of allergens and irritants and ...
Leto: 2006 Vir: dLib.si Digitalna knjižnica Slovenije
Systemic and airway oxidative stress in competitive swimmers
Sabina Škrgat-Kristan, Peter Korošec, Izidor Kern, Mira Šilar, Julij Gyula Šelb, Matjaž Fležar, Robert Marčun
Izvirni znanstveni članek
Oznake: bronchial hyperresponsiveness;competitive swimmers;training;
Background: The environment in swimming pools, which contain chlorine, might interact with the airway epithelium, resulting in oxidative stress and/or inflammation during high intensity training periods. Methods: We evaluated pulmonary functional (metacholine challenge test, FEV1 and VC), cellular ( ...
Leto: 2018 Vir: Digitalni repozitorij raziskovalnih organizacij Slovenije
Stališče do obravnave akutnega poslabšanja kronične obstruktivne pljučne bolezni (apKOPB)
Sabina Škrgat-Kristan, Jurij Šorli, Viktorija Tomič, Ema Mušič, Bojana Beović, Stanislav Šuškovič, Mitja Košnik, Franc Šifrer, Nena Kopčavar Guček, Katarina Osolnik, Renato Eržen, Matjaž Fležar, Davorina Petek
Strokovni članek
Oznake:
Leto: 2009 Vir: dLib.si Digitalna knjižnica Slovenije
Št. zadetkov: 9
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