Št. zadetkov: 43
Pregledni znanstveni članek
Oznake:
rak jajčnikov;estrogeni;imunosupresivno mikrookolje;ovarian cancer;estrogens;immunosuppressive microenvironment;
Ovarian cancer is a heterogeneous disease affecting the aging ovary, in concert with a complex network of cells and signals, together representing the ovarian tumor microenvironment. As in the "Schrödinger's cat" thought experiment, the context-dependent constituents of the-by the time of diagnosis- ...
Leto:
2021
Vir:
Medicinska fakulteta (UL MF)
Pregledni znanstveni članek
Oznake:
endocrinology;endometrial cancer;androgen hormones;
Endometrial cancer (EC) is a gynecological pathology that affects the uterine inner lining. In recent years, genomic studies revealed continually evolving muta- tional landscapes of endometrial tumors that hold great potential for tailoring therapeutic strategies. This review aims to broaden our kno ...
Leto:
2022
Vir:
Medicinska fakulteta (UL MF)
Pregledni znanstveni članek
Oznake:
nosečnice;intrakrinologija;rak endometrija;rak prostate;intracrinology;endometrial cancer;prostate cancer;
Local formation and action of estrogens have crucial roles in hormone dependent cancers and benign diseases like endometriosis. Drugs that are currently used for the treatment of these diseases act at the receptor (i.e., they interfere with the hormone receptor) and at the pre-receptor levels, targe ...
Leto:
2023
Vir:
Medicinska fakulteta (UL MF)
Izvirni znanstveni članek
Oznake:
endometrial cancer;Cimicifuga racemosa;ovarian cancer;
In postmenopausal women, estrogen levels exclusively depend on local formation from the steroid precursors dehydroepiandrosterone sulfate and estrone sulfate (E1-S). Reduced estrogen levels are associated with menopausal symptoms. To mitigate these symptoms, more women nowadays choose medicine of na ...
Leto:
2022
Vir:
Medicinska fakulteta (UL MF)
Izvirni znanstveni članek
Oznake:
cartilage oligomeric matrix protein;transforming growth factor-b-induced protein ig-h3;cancer antigen 125;blood biomarkers;endometriosis;non-invasive diagnosis;diagnostic algorithm;receiver operating characteristic curve;sensitivity;specificity;
STUDY QUESTION: Can cartilage oligomeric matrix protein (COMP) and transforming growth factor-b-induced protein ig-h3 (TGFBI) alone or in combination with cancer antigen 125 (CA-125) be considered as potential blood biomarkers of endometriosis? SUMMARY ANSWER: The results of this study indicate that ...
Leto:
2023
Vir:
Medicinska fakulteta (UL MF)
Izvirni znanstveni članek
Oznake:
breast cancer;endometrial cancer;ovarian cancer;estrane derivatives;cytotoxicity;
Hormone-dependent cancers such as breast, uterine, and ovarian cancers account for more than 35% of all cancers in women. Worldwide, these cancers occur in more than 2.7 million women/year and account for 22% of cancer-related deaths/year. The generally accepted mechanism for the pathophysiology of ...
Leto:
2023
Vir:
Medicinska fakulteta (UL MF)
Izvirni znanstveni članek
Oznake:
high-grade serous ovarian cancer;immunohistochemistry;survival;
Although aldo-keto reductases (AKRs) have been widely studied in cancer, no study to date has examined the roles of AKR family 1 members B1 (AKR1B1) and B10 (AKR1B10) in a large group of ovarian cancer patients. AKR1B1 and AKR1B10 play a significant role in inflammation and the metabolism of differe ...
Leto:
2022
Vir:
Medicinska fakulteta (UL MF)
Pregledni znanstveni članek
Oznake:
The 17beta-hydroxysteroid dehydrogenases (17beta-HSDs) have important roles inthe regulation of steroid hormone actions through their catalysis of the oxidation or reduction of estrogens and androgens at position 17. To date, 11 different human 17beta-HSDs have been described Dysfunction of the huma ...
Leto:
2005
Vir:
dLib.si Digitalna knjižnica Slovenije
Doktorska disertacija
Oznake:
ovarijska endometrioza;imunski sistem;vnetje;citokini;biglikan;PLA2G2A;biološki označevalci;prenos Western;ELISA;disertacije;
Preučevanje možnih bioloških označevalcev pri ovarijski endometriozi
Leto:
2013
Vir:
Medicinska fakulteta (UL MF)
Diplomsko delo
Oznake:
rak endometrija;17[beta]-hidroksisteroid-dehidrogenaza;AKR1C3;estradiol;
Študije izražanja 17[beta]-hidroksisteroid-dehidrogenaze AKR1C3 pri raku endometrija
Leto:
2007
Vir:
Medicinska fakulteta (UL MF)