diplomska naloga
Tanja Fajfar (Author), Željko Knez (Mentor), Zoran Novak (Co-mentor)

Abstract

Naravni polimeri so se uveljavili kot obetaven material za sintezo in pripravo nanoporoznih delcev. Eden izmed najbolj raziskanih in uporabljenih naravnih polimerov je alginat, ki ga pridobivajo iz različnih vrst rjavih morskih alg. Zaradi sposobnosti geliranja in nabrekanja ter nekaterih drugih lastnosti je zelo primeren kot nosilec aktivnih učinkovin. V diplomski nalogi smo pripravili 1,5%; 2% in 2,5% alginatne gele: monolite, ki smo jih narezali na koščke in sferične alginatne kroglice, v katere smo vezali nikotinsko kislino kot aktivno substanco. Nato smo jih superkritično posušili s CO2 in tako dobili organske biorazgradljive aerogele.

Keywords

alginat;aerogeli;superkritično sušenje;nikotinska kislina;škrob;nadzorovano sproščanje;

Data

Language: Slovenian
Year of publishing:
Source: Maribor
Typology: 2.11 - Undergraduate Thesis
Organization: UM FKKT - Faculty of Chemistry and Chemical Engineering
Publisher: [T. Fajfar]
UDC: 544.774.2-961(043.2)
COBISS: 14995990 Link will open in a new window
Views: 2360
Downloads: 308
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Other data

Secondary language: English
Secondary title: Synthesis and application of biodegradable organic aerogels as drug carriers
Secondary abstract: Natural polymers have established themselves as a promising material for the synthesis and preparation of nanoporous particles. One of the most researched and used natural polymers is alginate, which is obtained from different types of brown seaweed. Due to its ability to gel and swell and some other properties, alginate is very suitable as a carrier for active ingredients. In this thesis, we prepared 1.5%, 2% and 2.5% alginate gels: monoliths, which were cut into small pieces and spherical alginate beads, in which we introduce nicotinic acid as active substance. We then dried by supercritical CO2 and thus obtained biodegradable organic aerogels.
Secondary keywords: alginate;aerogels;supercritical drying;nicotinic acid;starch;controlled release;
URN: URN:SI:UM:
Type (COBISS): Undergraduate thesis
Thesis comment: Univ. v Mariboru, Fak. za kemijo in kemijsko tehnologijo
Pages: XI, 50 f.
Keywords (UDC): mathematics;natural sciences;naravoslovne vede;matematika;chemistry;crystallography;mineralogy;kemija;physical chemistry;fizikalna kemija;chemistry of surface phenomena and colloids;kemija površinskih pojavov in koloidov;
ID: 1005036