(diplomsko delo)
Eva Rotman (Author), Miljenko Križmarić (Mentor), Jurij Dolenšek (Co-mentor)

Abstract

Uvod: Možgani za svoje delovanje potrebujejo stalen dotok krvi. V določenih kliničnih situacijah pa je potrebno zmanjšati pretok krvi, ob tem je nujno spremljanje količin kisika. Z raziskavo smo želeli ugotoviti, ali se lahko s tehniko bližnje infrardeče spektroskopije zazna spremembe kisika v možganih pri kratkotrajni hiperventilaciji in hipoventilaciji. Metode: V teoretičnem delu smo pridobili podatke z deskriptivno metodo dela, v empiričnem pa smo uporabili kvantitativno metodo z namenskim vzorcem. Regionalno nasičenost kisika v možganih smo izmerili s spektroskopijo v bližnjem infrardečem polju. Med preizkusom hiperventilacije in hipoventilacije smo spremljali vrednosti dihanja, pulza, PETCO2 in SpO2. Rezultati: V času hiperventilacije so se vrednosti rSO2 znižale za 2 % v primerjavi z začetnimi vrednostmi. Padanje se je nadaljevalo v času počitka 1, kljub temu, da se je PETCO2 zviševal. V času hipoventilacije počitka 3 smo opazili ponovno zviševanje rSO2 parametra. Diskusija in zaključek: S testom hiperventilacije in hipoventilacije smo prikazali vpliv PETCO2 na spreminjanje rSO2. Glavni mehanizem, ki je odgovoren za zmanjšanje rSO2 pri hiperventilaciji, je hipokapnija.

Keywords

možganska prekrvavitev;avtoregulacija;hipokapnija;vazokonstrikcija;spektroskopija v bližnjem infrardečem polju;

Data

Language: Slovenian
Year of publishing:
Typology: 2.11 - Undergraduate Thesis
Organization: UM FZV - Faculty of Health Sciences
Publisher: [E. Rotman]
UDC: 616.8(043.2)
COBISS: 2352292 Link will open in a new window
Views: 977
Downloads: 134
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Other data

Secondary language: English
Secondary title: Dynamics of cerebral oxygenation when performing hyperventilation and hypoventilation
Secondary abstract: Introduction: Our brain require constant supply of blood for its functioning. But in some clinical situations it is indispensable to reduce blood flow. In these cases it is necessary to monitor the oxygen level in the brain. With the research we wanted to find out wheter near-infrared spectroscopy detects changes of oxygen in brain during short term hyperventilation and hypoventilation. Methods: In the theoretical part we obtained data with the descriptive method whereas in the empirical part we used a quantitative method with a purposive sample. The regional oxygen saturation in the brain was measured with near-infrared spectroscopy. We monitored values of respiration, pulse, PETCO2 and SpO2 during the test of hyperventilation and hypoventilation. Results: In hyperventilation the rSO2 values were decreased by 2 % from the baseline. The decline continued through the 1st rest despite the elevating PETCO2. In hypoventilation and the 3rd period of rest that we noticed an increase of rSO2 parameters. Discussion: The hyperventilation and hypoventilation test showed the effect of PETCO2 on the alteration of rSO2 parameter. The main mechanism, responsible for the decrease of rSO2 in hyperventilation is hypocapnia.
Secondary keywords: cerebral blood flow;autoregulation;hypocapnia;vasoconstiction;near-infrared spectroscopy;
URN: URN:SI:UM:
Type (COBISS): Bachelor thesis/paper
Thesis comment: Univ. v Mariboru, Fak. za zdravstvene vede
Pages: IV, 23 f.
ID: 10858881