diplomsko delo
Urška Kralj (Author), Irena Oven (Mentor), Irena Oven (Thesis defence commission member), Damjana Drobne (Thesis defence commission member), Polona Jamnik (Thesis defence commission member)

Abstract

Alergija na hrano je potencialno smrtno nevarna imunska reakcija, ki jo običajno sprožijo neškodljivi antigeni proteinov hrane. Razširjenost alergij na hrano raste, do danes pa ne obstaja nobena odobrena terapija zdravljenja razen izogibanja alergena hrane ter zdravljenja akutnih alergijskih reakcij z vbrizganjem epinefrina. Oralna imunoterapija predstavlja obetajočo terapevtsko alternativo, kjer pacienti uživajo majhne, a postopoma večje količine alergena tekom več mesecev, vendar je povezana s pogostimi alergijskimi reakcijami. Medtem ko je desenzibilizacija ali zmanjšana reaktivnost na alergen hrane, dosežena pogosto, indukcija dolgotrajne tolerance še ni bila vzpostavljena. V delu se bom osredotočila na glavne dosežke in nedavne napredke v oralni imunoterapiji za zdravljenje pogostih alergij na hrano, kot so arašidi, kravje mleko, jajca in pšenica.

Keywords

oralna imunoterapija;alergija na hrano;zdravljenje;alergeni;toleranca;

Data

Language: Slovenian
Year of publishing:
Typology: 2.11 - Undergraduate Thesis
Organization: UL BF - Biotechnical Faculty
Publisher: [U. Kralj]
UDC: 57.083.3:612.39(043.2)
COBISS: 9058169 Link will open in a new window
Views: 1210
Downloads: 292
Average score: 0 (0 votes)
Metadata: JSON JSON-RDF JSON-LD TURTLE N-TRIPLES XML RDFA MICRODATA DC-XML DC-RDF RDF

Other data

Secondary language: English
Secondary title: Oral immunotherapy for food allergy
Secondary abstract: Food allergy is potentially life-threatning immune reaction, triggered by normally innocous food protein antigens. The prevalence of food allergy is rising, but there is no approved therapy apart from avoidance of allergenic foods and treatment of acute allergic reactions with injectable epinephrine. Oral immunotherapy is a promising therapeutic alternative, in which patients consume small, but gradually increasing alergen doses over many months, but it is associated with frequent allergic reactions. While desensitization, or reduced reactivity to food alergens, is often achieved, the induction of long term tolerance has not yet been established. In this work I will focus on main acchivements and recent progres in oral immunotherapy for treatment of common food alergies, such as peanut, cow's milk, hen's egg and wheat.
Secondary keywords: oral immunotherapy;food allergy;treatment;allergens;tolerance;
Type (COBISS): Bachelor thesis/paper
Study programme: 0
Embargo end date (OpenAIRE): 1970-01-01
Thesis comment: Univ. v Ljubljani, Biotehniška fak., Študij biotehnologije
Pages: VI, 18 str.
ID: 10958070