magistrsko delo
Jure Lapajne (Author), Primož Ziherl (Mentor)

Abstract

V delu predstavimo model vesikla v cilindrični ograditvi. Model temelji na vesiklih, sestavljenih iz geometrijsko preprostih oblik, za katere lahko analitično izračunamo površino, reducirano razliko površin monoslojev in upogibno energijo. Ideje za mo- delske oblike smo dobili ob pregledovanju slik mitohondrija pod elektronskim mikroskopom in elektronskih tomogramov. Vsaki obliki pripišemo lokalno in nelokalno upogibno energijo, upoštevamo pa tudi medmembransko interakcijo, ki je sorazmerna medmembranski kontaktni površini. Na koncu predstavimo fazne diagrame ter jih povežemo s prehodi med ortodoksnim in kondenziranim stanjem mitohondrija.

Keywords

biofizika;celične strukture;lipidni vesikli;ograjeni vesikli;mitohondriji;upogibna energija;

Data

Language: Slovenian
Year of publishing:
Typology: 2.09 - Master's Thesis
Organization: UL FMF - Faculty of Mathematics and Physics
Publisher: [J. Lapajne]
UDC: 577.35
COBISS: 3258724 Link will open in a new window
Views: 722
Downloads: 185
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Other data

Secondary language: English
Secondary title: Lipid vesicles in cylindrical confinement
Secondary abstract: In this thesis we present a simple model of a vesicle confined in a cylindrical cavity. The model is based on vesicles assembled from simple geometrical shapes for which analytical expressions for surface, area difference of monolayers and bending energy are easily calculated. Shapes used in the presented model are inspired by electron micrographs and electron tomograms of mitochondria. For each shape we calculate the local and non-local bending energy, and we also include the intermembrane interaction, which is proportional to intermembrane contact area. We present the phase diagrams and connect them with the transition between the orthodox and the condensed state in mitochondria.
Secondary keywords: biophysics;subcellular structures;lipid vesicles;confined vesicles;mitochondria;bending energy;
Type (COBISS): Master's thesis/paper
Study programme: 0
Embargo end date (OpenAIRE): 1970-01-01
Thesis comment: Univ. v Ljubljani, Fak. za matematiko in fiziko, Oddelek za fiziko
Pages: 70 str.
ID: 10958884