diplomsko delo
Katarina Košnjek (Author), Tatjana Pirman (Reviewer), Klemen Potočnik (Mentor)

Abstract

Selekcija je še do nedavno temeljila na meritvah in ocenah posameznih lastnosti, ki so bile pridobljene na podlagi fenotipa živali in njihovih sorodnikov. Z napredkom na področju molekularne biologije in genetike se je to spremenilo. Genomska selekcija je relativno nova metoda, ki temelji na uporabi genomskih informacij. Ta oblika selekcije je mogoča zaradi odkritja polimorfizmov na enem nukleotidu. Ti so bili odkriti s pomočjo sekvenciranja genoma, kar je omogočilo genotipizacijo velikega števila SNP. Govedorejsko razvite države so genomsko selekcijo uspešno vpeljale v svoje rejske programe. To je k uporabi genomskih informacij spodbudilo tudi rejske organizacije, ki se ukvarjajo z vzrejo športnih konj. Največja prednost uporabe sodobnejše tehnologije se kaže v skrajšanju generacijskega intervala in posledično doseganju večje intenzivnosti selekcije, celo pri lastnostih, ki imajo majhen dednostni delež. Zaradi majhnih populacij pri konjih, je brez povezovanja rejskih organizacij zelo zahtevno sestaviti dovolj veliko referenčno populacijo. Posledično so rejske organizacije pričele z uporabo genomskih informacij, kjer ni potrebno imeti lastne referenčne populacije. To je za učinkovitejše preprečevanje parjenja v sorodstvu, ki je pri konjih pogostejše zaradi majhnih populacij ter pri ugotavljanju monogenskih značilnosti, zlasti genskih napak. Namen diplomskega dela je predstaviti možnosti uporabe genomskih informacij pri selekciji konj.

Keywords

konji;genomska selekcija;kvantitativne lastnosti;kvalitativne lastnosti;Interstallion;diplomske naloge;

Data

Language: Slovenian
Year of publishing:
Typology: 2.11 - Undergraduate Thesis
Organization: UL BF - Biotechnical Faculty
Publisher: [K. Košnjek]
UDC: 636.1:575(043.2)
COBISS: 4128648 Link will open in a new window
Views: 710
Downloads: 204
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Other data

Secondary language: English
Secondary title: Use of genomic information in horse selection
Secondary abstract: Until recently breeding selection was based on measurements and assesments acquired from the fenotypes of animals and their relatives. However based on the fenotypes of animals and their relatives genetics it has become easier to select for desirable traits. Genomic selection is a relatively new method, based on single nucleotide polymorphism. Single nucleotide polymorphism (SNP) is a variation of a single nucleotide at specific position in genome and has been discovered with help of genome sequencing. With development of new methods genome sequencing became more affordable and larger data sets were being analysed. Countries where livestock production is an important part of the economy, have successfully implemnted genomic selection into their breeding programs. This in turn influenced horse breeding organizations to start using genomic selection as well. The biggest advantage of using modern technology is in shortening of generation interval and consequently more intensive selection, even for traits with low heritability. Due to small horse population creating a large reference population can be difficult. Therefore breeding organizations started implementing the method of using genomic informations where the use of large reference population (of related animals) was not needed. This enabled breeders to avoid breeding relatives, which is problematic in horses because of small populations and to test for monogenetic traits, especially genetic mutations. The purpose of B. Sc. Thesis is to present different possibilities of the use of genomic informations in horse breeding selection.
Secondary keywords: horses;genomic selection;Interstallion;quantitative traits;qualitative traits;
Type (COBISS): Diploma project paper
Study programme: 0
Embargo end date (OpenAIRE): 1970-01-01
Thesis comment: Univ. v Ljubljani, Biotehniška fak., Oddelek za zootehniko
Pages: VII, 15 str.
ID: 10961148