Sinteza izbranih amidov piruvične kisline

diplomsko delo

Klemen Kozlovič (Author), Krištof Kranjc (Mentor)

Abstract

Sledeče diplomsko delo opisuje pripravo štirih različnih amidov piruvične kisline. Sinteze so bile izvedene preko njenega kislinskega klorida (ki je bil iz piruvične kisline pripravljen s pomočjo oksalil klorida), ki je v naslednji stopnji z različnimi amini (dietilamin, cikloheksilamin, anilin, 4-metoksianilin) reagiral do različno substituiranih amidov. Sintetizirane amide smo okarakterizirali s pomočjo IR spektroskopije, 1H NMR spektroskopije, HRMS ter jim izmerili temperaturo tališča.

Keywords

organska sinteza;piruvična kislina;amidi;piruvatni ion;oksalil klorid;kislinski kloridi;Schotten-Baumannovi pogoji sinteze amidov;spektroskopija;diplomska dela;

Data

Language:	Slovenian
Year of publishing:	2019
Typology:	2.11 - Undergraduate Thesis
Organization:	UL FKKT - Faculty of Chemistry and Chemical Technology
Publisher:	[K. Kozlovič]
UDC:	547.48.057(043.2)
COBISS:	1538310083
Views:	743
Downloads:	206
Average score:	0 (0 votes)
Metadata:

Other data

Secondary language:	English
Secondary title:	Synthesis of selected amides of pyruvic acid
Secondary abstract:	The following diploma thesis describes the synthesis of four different amides of pyruvic acid. The reactions were carried out via corresponding acid chloride (prepared from pyruvic acid with the addition of oxalyl chloride) that was in the next step reacted with a selection of amines (diethylamine, cyclohexylamine, aniline, 4-methoxyaniline) yielding variously substituted amides. The final products were characterised using IR spectroscopy, 1H NMR spectroscopy, HRMS and with melting points measurement.
Secondary keywords:	pyruvic acid;oxalyl chloride;acid chlorides;Schotten-Baumann conditions of amides synthesis;spectroscopy;
Type (COBISS):	Bachelor thesis/paper
Study programme:	1000373
Embargo end date (OpenAIRE):	1970-01-01
Thesis comment:	Univ. v Ljubljani, Fak. za kemijo in kemijsko tehnologijo, UNI Kemija
Pages:	30 str.
ID:	11215363