diplomsko delo
Nataša Šuklje (Author), Marjan Jereb (Mentor)

Abstract

Halkogeni derivati so pomembne spojine. V organski kemiji lahko služijo kot intermediati v sintezi, mnoge halkogene spojine pa imajo tudi biološko delovanje. V zadnjih letih se je organska kemija selena in telurja zelo razvila. Selenov atom je lahko v organoselenove spojine vključen kot elektrofil ali nukleofil. Poznamo elektrofilne kot tudi nukleofilne selenove reagente. V diplomskem delu bom opisala nekatere metode s katerimi jih lahko sintetiziramo. Selenocianate lahko pripravimo z direktnim ali indirektnim seleniliranjem. V kemiji so uporabni kot intermediati za nadaljnje sinteze. Zaradi svojih različnih bioloških lastnosti pa se lahko uporabljajo tudi v kemoterapiji. Tako kot organoselenova, ima tudi organotelurjeva kemija široko področje za nadaljnji razvoj. Tako npr. selen in telur vsebujejo 5-arilhalkogenoalkil-1H-tetrazoli, ki imajo protiglivično delovanje.

Keywords

organoselenove spojine;organotelurjeve spojine;halkogeni elementi;sinteza organoselenocianatov;biološke aktivnosti;diplomske naloge;

Data

Language: Slovenian
Year of publishing:
Typology: 2.11 - Undergraduate Thesis
Organization: UL FKKT - Faculty of Chemistry and Chemical Technology
Publisher: [N. Šuklje]
UDC: 547.1'123:547.1'124(043.2)
COBISS: 28691715 Link will open in a new window
Views: 306
Downloads: 67
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Other data

Secondary language: English
Secondary title: Synthesis of some chalcogenated derivatives
Secondary abstract: Chalcogen derivatives are important compounds. In organic chemistry they can serve as intermediates in synthesis, and many of chalcogen compounds also exhibit biological activity. In recent years, chemistry using selenium and tellurium has evolved greatly. Selenium atom can be incorporated into compounds as a nucleophile or an electrophile. Electrophilic as well as nucleophilic selenium reagents are known. In this thesis I will describe some methods by which we can synthesise them. Selenocyanates can be prepared by direct or indirect selenocyanation. In chemistry they can be used as intermediates for further synthesis. Due to their various biological properties, they can also be used in chemotherapy. Like organoselenes, organotellurium chemistry has a wide field with greater possibilities for development. For example, selenium and tellurium containing 5-arylchalcogenoalkyl-1H-tetrazoles have displayed anifungal activity.
Secondary keywords: organoselenium compounds;organotellurium compounds;chalcogen elements;
Type (COBISS): Bachelor thesis/paper
Study programme: 1000374
Thesis comment: Univ. v Ljubljani, Fak. za kemijo in kemijsko tehnologijo
Pages: 41 str.
ID: 12029416