diplomsko delo
Žan Boček (Author), Aleš Ručigaj (Mentor)

Abstract

Hidrogeli so tema različnih raziskav predvsem zaradi njihovih sposobnosti zadrževanja in sproščanja farmacevtskih učinkovin, s čimer je mogoče nadzirano sproščanje teh učinkovin v specifičnem mesta v organizmu. Raziskave so usmerjene v načine priprave, ki bi omogočali prilagajanje lastnosti hidrogelov specifičnim načinom oziroma mestom uporabe. Obetaven material za pripravo naravnih hidrogelov je hitozana, ki je biorazgradljiv in biokompatibilen. Zaradi razširjenosti in preprostosti proizvodnje je dostopen v velikih količinah po nizkih cenah. Diplomsko delo obravnava vpliv, ki ga imajo alginat, celuloza in laponit na reološke lastnosti hidrogelov iz hitozana. Predstavljeni so različni načini priprave hidrogelov in modificirane lastnosti, ki so posledica kemijskih lastnosti in količine uporabljenega modifikatorja.

Keywords

hidrogeli;hitozan;alginat;celuloza;laponit;reologija;sproščanje učinkovin;diplomska dela;

Data

Language: Slovenian
Year of publishing:
Typology: 2.11 - Undergraduate Thesis
Organization: UL FKKT - Faculty of Chemistry and Chemical Technology
Publisher: [Ž. Boček]
UDC: 678:532.135(043.2)
COBISS: 28021763 Link will open in a new window
Views: 337
Downloads: 104
Average score: 0 (0 votes)
Metadata: JSON JSON-RDF JSON-LD TURTLE N-TRIPLES XML RDFA MICRODATA DC-XML DC-RDF RDF

Other data

Secondary language: English
Secondary title: Influence of an additional modifier on the properties of chitosan hydrogels
Secondary abstract: Hydrogels are the subject of various studies, mainly due to their ability to retain and release pharmaceutical ingredients, thus allowing the controlled release of these ingredients at a specific site in the body. Research is focused on methods of preparation that would enable the adjustment of the properties of hydrogels to specific methods or areas of use. A promising material for the preparation of natural hydrogels is chitosan, which is biodegradable and biocompatible. Due to its prevalence and simple production it is available in large quantities at low prices. The thesis discusses the influence alginate, cellulose and laponite have on the rheological properties of chitosan hydrogels. Presented are different methods of hydrogel preparation and modified properties, which are the result of the chemical properties and amount of modifier used.
Secondary keywords: hydrogels;rheology;chitosan;drug delivery;
Type (COBISS): Bachelor thesis/paper
Study programme: 1000372
Thesis comment: Univ. v Ljubljani, Fak. za kemijo in kemijsko tehnologijo, UNI Kemijsko inženirstvo
Pages: 34 f.
ID: 12029424