diplomsko delo
Klemen Oman (Author), Aleš Ručigaj (Mentor)

Abstract

Nanoceluloza je material na osnovi celuloze, ki ima vsaj eno zmed svojih zunanjih dimenzij v nano območju. S svojo nizko težo, veliko trdnostjo in biokompatibilnostjo je v zadnjem času postala izredno zanimiva na številnih področjih. Uporablja se kot osnova v hidrogelih, ki se v farmacevtski industriji uporabljajo za tarčno in kontrolirano sproščanje učinkovin v telesu ter njihovo dostavo. Hidrogeli so v splošnem tridimenzionalna polimerna omrežja, ki lahko absorbirajo in zadržijo velike količine vode. Raziskovalci poskušajo lastnosti hidrogelov izboljšati z zamreževanjem. Ločimo fizikalno in kemijsko zamreženje. Fizikalno zamreženi hidrogeli nastanejo z medmolekulskimi reverzbilnimi interakcijami, medtem ko kemijsko zamreženi hidrogeli nastanejo preko kovalentnih vezi.

Keywords

nanoceluloza;TEMPO oksidacija;hidrogeli;zamreževanje;transportni sistemi zdravil;diplomska dela;

Data

Language: Slovenian
Year of publishing:
Typology: 2.11 - Undergraduate Thesis
Organization: UL FKKT - Faculty of Chemistry and Chemical Technology
Publisher: [K. Oman]
UDC: 678.5:620.3(043.2)
COBISS: 31476739 Link will open in a new window
Views: 440
Downloads: 128
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Other data

Secondary language: English
Secondary title: Crosslinking methods of TEMPO modified nanocellulose used in drug delivery
Secondary abstract: Nanocellulose is a cellulose-based material that has at least one of its external dimensions in the nano range. With its low weight, high strength and biocompatibility, it has recently become extremely interesting in many areas. It is used as a base in hydrogels, which are used in the pharmaceutical industry for targeted and controlled release of active substances in the body and their delivery. Hydrogels are generally three-dimensional polymer networks that can absorb and retain large amounts of water. Scientists are trying to improve the properties of hydrogels by crosslinking. We distinguish between physical and chemical crosslinking. Physically crosslinked hydrogels are formed by intramolecular reversible interactions, while chemically crosslinked hydrogels are formed through covalent bonds.
Secondary keywords: nanocellulose;hydrogels;crosslinking;drug delivery systems;
Type (COBISS): Bachelor thesis/paper
Study programme: 1000372
Embargo end date (OpenAIRE): 1970-01-01
Thesis comment: Univ. v Ljubljani, Fak. za kemijo in kemijsko tehnologijo, UNI Kemijsko inženirstvo
Pages: 35 str.
ID: 12033031