Andreja Erman (Author), Peter Veranič (Author)

Abstract

The most frequent diseases of the urinary bladder are bacterial infections and bladder cancers. For both diseases, very high recurrence rates are characteristic: 50-80% for bladder cancer and more than 50% for bladder infections, causing loss of millions of dollars per year for medical treatment and sick leave. Despite years of searching for better treatment, the prevalence of bladder infections and bladder cancer remains unchanged and is even increasing in recent years. Very encouraging results in treatment of both diseases recently culminated from studies combining biopolymer chitosan with immunotherapy, and chitosan with antibiotics for treatment of bladder cancer and cystitis, respectably. In both pathways of research, the discoveries involving chitosan reached a successful long-lasting cure. The property of chitosan that boosted the effectivity of illness-specific drugs is its ability to enhance the accessibility of these drugs to the very sources of both pathologies that individual treatments without chitosan failed to achieve. Chitosan can thus be recognised as a very promising co-player in treatment of bladder cancer and bacterial cystitis.

Keywords

chitosan;biological activity;medical applications;

Data

Language: English
Year of publishing:
Typology: 1.02 - Review Article
Organization: UL MF - Faculty of Medicine
UDC: 577
COBISS: 33675993 Link will open in a new window
ISSN: 2073-4360
Views: 311
Downloads: 63
Average score: 0 (0 votes)
Metadata: JSON JSON-RDF JSON-LD TURTLE N-TRIPLES XML RDFA MICRODATA DC-XML DC-RDF RDF

Other data

Secondary language: Slovenian
Secondary keywords: hitozan;biološka dejavnost;medicinske aplikacije;
Type (COBISS): Article
Source comment: V datoteki založnikove različice članka (PDF) je navedena napačna številka članka (625). Prava številka članka (265) je navedena na pristajalni strani članka (URL). (Datum opombe: 28. 7. 2021)
Pages: str. 1-10
Volume: ǂVol. ǂ10
Issue: ǂno. ǂ3
Chronology: 2018
DOI: 10.3390/polym10030265
ID: 13181178