Predicting "Heart Age" using electrocardiography

Robyn L. Ball (Author), Alan H. Feiveson (Author), Todd T. Schlegel (Author), Vito Starc (Author), Alan R. Dabney (Author)

Abstract

Knowledge of a patient's cardiac age, or "heart age", could prove useful to both patients and physicians for better encouraging lifestyle changes potentially beneficial for cardiovascular health. This may be particularly true for patients who exhibit symptoms but who test negative for cardiac pathology. We developed a statistical model, using a Bayesian approach, that predicts an individual's heart age based on his/her electrocardiogram (ECG). The model is tailored to healthy individuals, with no known risk factors, who are at least 20 years old and for whom a resting 5 min 12-lead ECG has been obtained. We evaluated the model using a database of ECGs from 776 such individuals. Secondarily, we also applied the model to other groups of individuals who had received 5-min ECGs, including 221 with risk factors for cardiac disease, 441 with overt cardiac disease diagnosed by clinical imaging tests, and a smaller group of highly endurance-trained athletes. Model-related heart age predictions in healthy non-athletes tended to center around body age, whereas about three-fourths of the subjects with risk factors and nearly all patients with proven heart diseases had higher predicted heart ages than true body ages. The model also predicted somewhat higher heart ages than body ages in a majority of highly endurance-trained athletes, potentially consistent with possible fibrotic or other anomalies recently noted in such individuals.

Keywords

cardiac age;statistical model;electrocardiography;

Data

Language:	English
Year of publishing:	2014
Typology:	1.01 - Original Scientific Article
Organization:	UL MF - Faculty of Medicine
UDC:	616.1
COBISS:	31208153
ISSN:	2075-4426
Views:	339
Downloads:	52
Average score:	0 (0 votes)
Metadata:

Other data

Secondary language:	Slovenian
Secondary keywords:	starost srca;statistični model;elektokardiografija;
Type (COBISS):	Article
Pages:	str. 65-78
Volume:	ǂVol. ǂ4
Issue:	ǂiss. ǂ1
Chronology:	Mar. 2014
DOI:	10.3390/jpm4010065
ID:	13296260