Antioxidative effects of olive polyphenols compared to vitamin E in piglets fed a diet rich in N-3 PUFA

Jakob Leskovec (Author), Vida Rezar (Author), Alenka Nemec Svete (Author), Janez Salobir (Author), Alenka Levart (Author)

Abstract

The aim of the current study was to assess the antioxidative effects of the dietary supplementation of olive leaf extract (OLE) in different concentrations compared to those of vitamin E in piglets under conditions of dietary n-3 PUFA-induced oxidative stress. Forty-eight castrated male piglets (10.6 ± 0.99 kg) were fed the following experimental diets: Cont− (low-fat diet, no supplement), Cont+ (high linseed oil diet, no supplement), Vit-E (as Cont+, 105 IU vitamin E/day), OLE-1 (as Cont+, 3.84 mg hydroxytyrosol equivalents (HEQs)/day), OLE-2 (as Cont+, 38.4 mg HEQ/day), and OLE-3 (as Cont+, 96 mg HEQ/day). After 21 days of feeding, the experimental diets, blood and urine samples were collected to assess the extent of the oxidative stress. Results indicated that diet OLE-1 lowered the activity of gamma-glutamyl transferase, protected DNA (measured as DNA tail %) and altered urinary 8-hydroxy-2’-deoxyguanosine (8-OHdG). Dietary vitamin E lowered the levels of urinary F$_2$-isoprostanes, as well as of plasma malondialdehyde and γ-tocopherol, but raised the plasmatic α-tocopherol and altered the level of urinary 8-OHdG. In conclusion, only minor positive effects of dietary OLE on the oxidative stress parameters were observed. Additionally, OLE did not show concentration dependence.

Keywords

prašiči;pujski;prehrana živali;maščobne kisline;PUFA;olive;polifenoli;vitamini;vitamin E;

Data

Language:	English
Year of publishing:	2019
Typology:	1.01 - Original Scientific Article
Organization:	UL BF - Biotechnical Faculty
UDC:	636.4.084/.087
COBISS:	4204936
ISSN:	2076-2615
Views:	374
Downloads:	121
Average score:	0 (0 votes)
Metadata:

Other data

Secondary language:	Slovenian
Secondary keywords:	prašiči;pujski;prehrana živali;maščobne kisline;PUFA;olive;polifenoli;vitamini;vitamin E;
Type (COBISS):	Article
Pages:	str. 1-12, e 161
Volume:	ǂVol. ǂ9
Issue:	ǂno. ǂ4
Chronology:	2019
DOI:	10.3390/ani9040161
ID:	13394691