Microfluidic technology for clinical applications of exosomes

Florina Silvia Iliescu (Author), Danilo Vrtačnik (Author), Pavel Neuzil (Author), Ciprian Iliescu (Author)

Abstract

Exosomes, a type of nanovesicle, are distinct cellular entities specifically capable of carrying various cargos between cells. It has been hypothesized that exosomes, as an enriched source of biomolecules, may serve as biomarkers for various diseases. This review introduces general aspects of exosomes, presents the challenges in exosome research, discusses the potential of exosomes as biomarkers, and describes the contribution of microfluidic technology to enable their isolation and analysis for diagnostic and disease monitoring. Additionally, clinical applications of exosomes for diagnostic purposes are also summarized.

Keywords

mikrofluidika;eksosomi;klinične aplikacije;zunajcelični vezikli;rak;vnetje;microfluidics;exosomes;clinical applications;extracellular vesicles;cancer;inflammation;

Data

Language:	English
Year of publishing:	2019
Typology:	1.02 - Review Article
Organization:	UL FE - Faculty of Electrical Engineering
UDC:	616-006:621.38
COBISS:	12545876
ISSN:	2072-666X
Views:	209
Downloads:	64
Average score:	0 (0 votes)
Metadata:

Other data

Secondary language:	Slovenian
Secondary keywords:	mikrofluidika;eksosomi;klinične aplikacije;zunajcelični vezikli;rak;vnetje;
Type (COBISS):	Article
Pages:	str. 1-29
Volume:	ǂiss. ǂ6
Issue:	392
Chronology:	2019
DOI:	10.3390/mi10060392
ID:	13715156