(diplomsko delo)
Lara Beber (Author), Jasmina Nerat (Mentor)

Abstract

Uvod: V zadnjem desetletju se je bolnikom z revmatoidnim artritisom z uporabo biološke terapije omogočilo dejavno in kakovostnejše življenje, kljub neprijetni diagnozi. Na temo zdravljenja z biološko terapijo obstaja veliko dilem, ki bolnike z revmatoidnim artritisom spravljajo v zadrego. Namen zaključnega dela je ugotoviti, kako zdravljenje z biološkimi zdravili vpliva na kakovost življenja bolnikov z revmatoidnim artritisom. Metode: Uporabili smo deskriptivno metodo dela. Izvedli smo narativni pregled znanstvene in strokovne literature o obravnavani temi. Kot orodje za oceno kakovosti člankov smo uporabili piramido hierarhije dokazov in v tabelah predstavili značilnosti identificiranih študij. Na raziskovalno vprašanje smo odgovorili z metodo vsebinske analize in sinteze. Rezultati: Po vsebinski analizi devetih člankov ugotavljamo, da bolniki z revmatoidnim artritisom poudarjajo visoko zadovoljstvo z biološko terapijo. Izboljšave so prisotne tako na področju fizičnega kot čustvenega počutja. Vendar smo pri bolnikih prav tako ugotovili tudi pojav hude utrujenosti. Ta je prisotna kljub urejeni bolezni, kar pomeni, da biološka terapija ne zmanjša nujno vseh težav in je v nekaterih primerih sama vzrok za pojav zdravstvene težave kot neželenega učinka. Razprava in sklep: Kljub utrujenosti kot najpogostejšemu neželenemu učinku bioloških zdravil ugotavljamo ugoden vpliv biološke terapije na kakovost življenja bolnikov z revmatoidnim artritisom. Pomembno je, da so bolniki z revmatoidnim artritisom, ki so velikokrat tudi mladi ljudje, dobro seznanjeni z omejitvami in izboljšavami na področju kakovosti življenja. Le na ta način bodo lahko sprejeli pravilne odločitve o zdravljenju.

Keywords

revmatična bolezen;zdravljenje;biološka zdravila;vnetje;

Data

Language: Slovenian
Year of publishing:
Typology: 2.11 - Undergraduate Thesis
Organization: UM FZV - Faculty of Health Sciences
Publisher: [L. Beber]
UDC: 616.72-002.77-056.24(043.2)
COBISS: 90376451 Link will open in a new window
Views: 271
Downloads: 87
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Other data

Secondary language: English
Secondary title: Quality of life of the patients with rheumatoid arthritis on biological therapy
Secondary abstract: Introduction: In a decade, patients with rheumatoid arthritis have been able to live an active and quality life using biological therapy, despite an unpleasant diagnosis. There are many dilemmas connected with biological therapy that patients with rheumatoid arthritis find challenging to decide on. The purpose of the final work is to ascertain how treatment with biologic drugs affects the quality of life of patients with rheumatoid arthritis. Methods: We used a descriptive method. We performed a narrative review of the scientific and professional literature on the topic. As a tool for assessing the quality of articles, we used hierarchy of evidence pyramid and presented the characteristics of the identified studies in tables. We answered the research question used the content analysis and synthesis method.…………………………. Results: After a content analysis of nine articles, we found that rheumatoid arthritis patients exhibit high satisfaction with biological therapy. Improvements are present in physical and emotional well-being. Severe fatigue has been reported in rheumatoid arthritis patients on biological therapy. This is present despite regulation of the disease, which means that biological therapy does not necessarily reduce all problems and in some cases is itself the cause of a health problem as a side effect. Discussion and conclusion: Despite fatigue as the most common adverse reaction of biological medicines, we note the beneficial impact of biological therapy on the quality of life of rheumatoid arthritis patients. It is important that patients with rheumatoid arthritis, who are often young people, are well aware of the limitations and improvements in quality of life. Only then will they be able to make the right decisions about the treatment.
Secondary keywords: rheumatic disease;treatment;biological drugs;inflammation;
Type (COBISS): Bachelor thesis/paper
Thesis comment: Univ. v Mariboru, Fak. za zdravstvene vede
Pages: V, 27 f.
ID: 13818647