Ita Junkar (Author), Metka Benčina (Author), Aleš Iglič (Author), Miran Mozetič (Author)

Abstract

Crystallization alters the characteristics of TiO$_2$ nanosurfaces, which consequently influences their bio-performance. In various biomedical applications, the anatase or rutile crystal phase is preferred over amorphous TiO$_2$. The most common crystallization technique is annealing in a conventional furnace. Methods such as hydrothermal or room temperature crystallization, as well as plasma electrolytic oxidation (PEO) and other plasma-induced crystallization techniques, present more feasible and rapid alternatives for crystal phase initiation or transition between anatase and rutile phases. With oxygen plasma treatment, it is possible to achieve an anatase or rutile crystal phase in a few seconds, depending on the plasma conditions. This review article aims to address different crystallization techniques on nanostructured TiO$_2$ surfaces and the influence of crystal phase on biological response. The emphasis is given to electrochemically anodized nanotube arrays and their interaction with the biological environment. A short overview of the most commonly employed medical devices made of titanium and its alloys is presented and discussed.

Keywords

titanium oxide;nanostructure;crystalline phase;biocompatibility;surface modification;

Data

Language: English
Year of publishing:
Typology: 1.02 - Review Article
Organization: UL FE - Faculty of Electrical Engineering
UDC: 620.3
COBISS: 19160835 Link will open in a new window
ISSN: 2079-4991
Views: 226
Downloads: 67
Average score: 0 (0 votes)
Metadata: JSON JSON-RDF JSON-LD TURTLE N-TRIPLES XML RDFA MICRODATA DC-XML DC-RDF RDF

Other data

Type (COBISS): Article
Pages: str. 1121-1-1121-23
Volume: ǂVol. ǂ10
Issue: ǂno. ǂ6
Chronology: 2020
DOI: 10.3390/nano10061121
ID: 14067381