Emanuela Boštjančič (Author), Željka Večerić-Haler (Author), Nika Kojc (Author)

Abstract

MicroRNAs (miRNAs) are members of the non-coding regulatory RNA family that play pivotal roles in physiological and pathological conditions, including immune response. They are particularly interesting as promising therapeutic targets, prognostic and diagnostic markers due to their easy detection in body fluids and stability. There is accumulating evidence that different miRNAs provide disease-specific signatures in liquid samples of distinct kidney injuries. Using experimental models and human samples, there have been numerous suggestions that immunerelated miRNAs are also important contributors to the development of different kidney diseases as well as important markers for monitoring response after kidney transplantation. However, there are limited data for understanding their function in the molecular pathways of allograft pathologies. In our review, we focused on microRNAs that are related to different aspects of immune response after kidney transplantation.

Keywords

mikroRNA (miRNA);presaditev ledvic;imunski odziv;microRNA (miRNA);kidney transplantation;immune response;

Data

Language: English
Year of publishing:
Typology: 1.02 - Review Article
Organization: UL MF - Faculty of Medicine
UDC: 616.6
COBISS: 76937219 Link will open in a new window
ISSN: 2218-273X
Views: 83
Downloads: 34
Average score: 0 (0 votes)
Metadata: JSON JSON-RDF JSON-LD TURTLE N-TRIPLES XML RDFA MICRODATA DC-XML DC-RDF RDF

Other data

Secondary language: Slovenian
Secondary keywords: mikroRNA (miRNA);presaditev ledvic;imunski odziv;
Type (COBISS): Article
Pages: str. 1-15
Volume: ǂVol. ǂ11
Issue: ǂno. ǂ8
Chronology: 2021
DOI: 10.3390/biom11081198
ID: 14956886