Pregled in pomen metabolitov probiotikov

(magistrsko delo)

Marina Koren (Author), Sabina Fijan (Mentor), Dušanka Mičetić-Turk (Co-mentor)

Abstract

Uvod: S sistematičnim pregledom literature po metodi PRIZMA smo razvrščali probiotike glede na metabolite. Zaradi pozitivnih učinkov probiotikov na zdravje ljudi in preventivo pred boleznimi smo želeli raziskati, katere metabolite tvorijo in v katere skupine jih lahko razvrstimo. Z magistrskim delom smo želeli odgovoriti na tri raziskovalna vprašanja, ki so se nam porajala ob pregledu literature. Metode: Podatke smo zbirali iz slovenske in tuje literature, ki je morala biti v angleškem jeziku. Iskali smo jo v štirih različnih podatkovnih bazah strokovnih člankov s pomočjo ključnih besed in Boolovih operaterjev. Med vsemi 9.713 članki smo nato s pomočjo diagrama po priporočilih PRISMA pregledali in uporabili 49 virov literature, med katerimi so bili pregledni in izvirni znanstveni članki. Rezultati: Ugotovili smo, da obstaja veliko različnih metabolitov probiotikov. Nekateri metaboliti so bolj raziskani kot drugi. Metabolite smo razdelili na bakteriocine, kratkoverižne in druge maščobne kisline ter druge metabolite. Ugotovili smo, da določene bakteriocine tvorijo probiotiki istega rodu, na primer plantaricin, pediocin, gasericin in koagulin. Razprava in sklep: Na podlagi rezultatov lahko tudi sklepamo, da lahko vsak probiotik, ki tvori značilen metabolit, po njem tudi identificiramo in prepoznamo. Metaboliti probiotikov lahko pomagajo pri preprečevanju in zdravljenju mnogih bolezni.

Keywords

probiotiki;metaboliti probiotikov;bakteriocini;kratkoverižne maščobne kisline;

Data

Language:	Slovenian
Year of publishing:	2022
Typology:	2.09 - Master's Thesis
Organization:	UM FZV - Faculty of Health Sciences
Publisher:	[M. Koren]
UDC:	613.292:601.2:577.121(043.2)
COBISS:	110075395
Views:	107
Downloads:	24
Average score:	0 (0 votes)
Metadata:

Other data

Secondary language:	English
Secondary title:	Review and significance of probiotic metabolites
Secondary abstract:	Introduction: With a systematic review of literature using the PRISMA method, we classified probiotics with regard to metabolites. Due to the positive effects of probiotics on human health, we wanted to analyse, which metabolites they form and in which groups we can classify them. With the master’s thesis, we wanted to answer three research questions that arose during the review of literature. Methods: We collected the data from Slovenian and English literature, which had to be in English. We searched for it in four different databases of professional articles with the help of keywords and Boolean operators. Out of 9.713 articles, we then used a diagram according to PRISM recommendations to review and finally use 49 sources of literature, among which were transparent and original scientific articles. Results: We found that there are various metabolites of probiotics. Some metabolites are more researched then others. We divided the metabolites into bacteriocins, short chain fatty acids and other metabolites. We found that certain bacteriocins are formed by probiotics of the same genus, for instance plantaricin, pediocin, gasericin and coagulin. Discussion and conclusion: Based on the results, we can also conclude that each probiotic, which forms a characteristic metabolite, can be identified and recognized by it. Metabolites of probiotics can help in the prevention and treatment of many diseases.
Secondary keywords:	probiotics;probiotic metabolites;bacteriocins;short chain fatty acid;Probiotics;Probiotiki;
Type (COBISS):	Master's thesis/paper
Thesis comment:	Univ. v Mariboru, Fak. za zdravstvene vede
Pages:	IV, 49 f., 5 f. pril.
ID:	15005995