ǂan ǂupdate
Maša Kenda (Author), Nina Kočevar Glavač (Author), Milan Nagy (Author), Marija Sollner Dolenc (Author)

Abstract

Depression, anxiety, stress, and other mental disorders, which are on the rise worldwide, are indications that pharmacological therapy can have serious adverse effects, which is why many patients prefer to use herbal products to treat these symptoms. Here, we reviewed plants and products derived from them that are commonly used for the above indications, focusing on clinical data and safety profiles. While lavender, hops, maypop, lemon balm, and valerian have consistently been shown in clinical trials to relieve mild forms of neurological disorders, particularly depression, anxiety, and stress, currently available data do not fully support the use of peppermint for anxiety disorders and depression. Recent studies support the use of saffron for depression; however, its toxicological profile raises safety concerns. St. John’s wort is effective in alleviating mild to moderate depression; however, careful use is necessary particularly due to possible interactions with other drugs. In conclusion, more studies are needed to validate the mechanism of action so that these plants can be used successfully and safely to alleviate or eliminate various mental disorders.

Keywords

centralni živčni sistem;anksioznost;central nervous system;depression;anxiety;insomnia;medicinal plants;

Data

Language: English
Year of publishing:
Typology: 1.02 - Review Article
Organization: UL FFA - Faculty of Pharmacy
UDC: 582:615.322
COBISS: 121583363 Link will open in a new window
ISSN: 1420-3049
Views: 9
Downloads: 7
Average score: 0 (0 votes)
Metadata: JSON JSON-RDF JSON-LD TURTLE N-TRIPLES XML RDFA MICRODATA DC-XML DC-RDF RDF

Other data

Secondary language: Slovenian
Secondary keywords: Zdravilne rastline;Nespečnost;Depresija (medicina);
Type (COBISS): Article
Pages: 20 str., art. 6021
Volume: ǂVol. ǂ27
Issue: ǂiss. ǂ18
Chronology: 2022
DOI: 10.3390/molecules27186021
ID: 16479179