magistrsko delo
Vanesa Močilnik (Author), Gorazd Drevenšek (Mentor)

Abstract

V nalogi smo analizirali podatke predhodno zajetih meritev elektroencefalografa (EEG) oseb z Brocovo afazijo, s katerimi smo želeli primerjati možgansko aktivnost pred in po rehabilitaciji. Želeli smo ugotoviti, ali je učinek terapije mogoče opaziti na EEG posnetkih po rehabilitaciji z analizo možganske povezljivosti, s frekvenčno analizo in analizo izvora možganske aktivnosti. Podatki so bili pridobljeni pri udeležencih, ki so reševali dve vrsti nalog delovnega spomina – naloge verbalnega delovnega spomina in naloge prostorskega delovnega spomina. Začeli smo s pripravo podatkov, nadaljevali pa s prikazom prostorske opredelitve izvora možganske aktivnosti. Dodatno smo izvedli tudi analizo moči posameznih frekvenčnih pasov – predvsem analizo teta valovanj (4–7 Hz) in gama valovanj (30–60 Hz). Za izračun možganske povezljivosti smo se osredotočili na funkcijsko možgansko povezljivost, ki temelji na statistični odvisnosti med signali. Cilj raziskave je bil podroben pregled in primerjava podatkov EEG pred in po rehabilitaciji. Večina izračunov možganske povezljivosti in moči teta ter gama valovanj je pokazala značilne razlike po rehabilitaciji – po rehabilitaciji je bilo mogoče opaziti razliko za vse kombinacije nalog in frekvenčnih pasov, p < 0,05. Na podlagi rezultatov menimo, da lahko sklepamo na učinkovitost terapije pri bolnikih z Brocovo afazijo s pomočjo analize možganske aktivnosti in povezljivosti.

Keywords

Brocova afazija;delovni spomin;EEG;možganska aktivnost;rehabilitacija;

Data

Language: Slovenian
Year of publishing:
Typology: 2.09 - Master's Thesis
Organization: UL PEF - Faculty of Education
Publisher: [V. Močilnik]
UDC: 616.89-008.434.5(043.2)
COBISS: 124134147 Link will open in a new window
Views: 3
Downloads: 0
Average score: 0 (0 votes)
Metadata: JSON JSON-RDF JSON-LD TURTLE N-TRIPLES XML RDFA MICRODATA DC-XML DC-RDF RDF

Other data

Secondary language: English
Secondary title: Brain activity comparison in patients with Broca's aphasia before and after rehabilitation
Secondary abstract: With the help of existing electroencephalography (EEG) data, we wished to compare brain activity in patients with Broca's aphasia before and after rehabilitation, and wanted to find out, whether the effect of therapy can be seen from the analysis of brain connectivity, frequency analysis and source localization. The data consists of patients’ EEG recordings while they were solving verbal and visuospatial working memory tasks. We started our research by first preprocessing the data, and continued by doing brain activity's source reconstruction, which is often called source localization. Moreover, we analysed the power spectrum of certain frequency bands – analysed the theta frequency band (4–7 Hz) and gamma frequency band (30–60 Hz). For brain connectivity measures we focused on the ones that calculate functional brain connectivity, so signals that are somehow statistically connected with each other. The goal of this research was to thoroughly analyse brain activity from the EEG data before and after rehabilitation, and see if we can conclude how effective the therapy was for patients with Broca's aphasia based on our results. Most of our calculations for brain connectivity and theta and gamma power showed a significant difference after rehabilitation – we noticed a difference for all combinations of the tasks and frequency bands after rehabilitation, p < 0.05. Based on our results, we conclude that we can infer the effect of rehabilitation from brain activity and connectivity analyses.
Secondary keywords: Kognitivna nevroznanost;Možgani;Afazija;Univerzitetna in visokošolska dela;
File type: application/pdf
Type (COBISS): Master's thesis/paper
Thesis comment: Univ. v Ljubljani, Pedagoška fak., Skupni interdisciplinarni program druge stopnje Kognitivna znanost, v sodelovanju z Universität Wien, Univerzita Komenského v Bratislave in Eötvös Loránd Tudományegyetem
Pages: 58 str.
ID: 16652356