Treatment of movement disorders using deep brain stimulation - illustrative case reports and technical notes

Tadej Strojnik (Author), Dušan Flisar (Author), Igor Drstvenšek (Author)

Abstract

Operative neuromodulation is the field of electrically or chemically altering the signal transmission in the nervous system by implanted devices in order to excite, inhibit or tune the activities of neurons or neural networks to produce therapeutic effects. Deep brain stimulation (DBS) is an important component of the therapy of movement disorders and has almost completely replaced high-frequency coagulation of brain tissue in stereotactic neurosurgery. This article presents the first DBS cases in Slovenia. In the article the technical features and adjustments of magnetic resonance (MR) imaging and development of a new microdrive, which was clinically successfully tested, are described and discussed.

Keywords

operative neuromodulation;microdrive;

Data

Language:	English
Year of publishing:	2012
Typology:	1.01 - Original Scientific Article
Organization:	UM FS - Faculty of Mechanical Engineering
Publisher:	Slovensko zdravniško društvo
UDC:	616.858-089
COBISS:	4294975
ISSN:	1318-0347
Parent publication:	Zdravniški vestnik
Views:	547
Downloads:	19
Average score:	0 (0 votes)
Metadata:

Other data

Secondary language:	Slovenian
Secondary title:	Stimulacija globokih možganskih jeder za zdravljenje motenj gibanja - prikaz primerov in tehničnih izboljšav
Secondary abstract:	Operacijska nevromodulacija je reverzibilna uporaba električne stimulacije ali dovajanje farmakoloških snovi v osrednji živčni sistem z vgradnjo naprave v bolnikov telo. Namen je spreminjati aktivnost živčnega sistema (ekscitacija, inhibicija ali prilagajanje nevronov ali nevronske mreže) za zdravljenje specifičnih stanj. Globoka možganska stimulacija (GMS) je pomembna metoda za zdravljenje gibalnih motenj in je skoraj popolnoma nadomestila visokofrekvenčno koagulacijo možganovine. V članku predstavljamo prve slovenske primere GMS. Predstavili smo tehnične posebnosti in prilagoditve pri uporabi magnetne resonance ter razvoj novega mikrovodila, ki smo ga uspešno klinično preizkusili.
Secondary keywords:	operativna nevromodulacija;mikrovodilo;Movement Disorders;Therapy;Motnje gibanja;Zdravljenje;Parkinson Disease;Parkinsonova bolezen;Deep Brain Stimulation;Globoka možganska jedra, stimulacija;Stereotaxic Techniques;Stereotaktične tehnike;Magnetic Resonance Imaging;Magnetna resonanca, prikaz;Surgical Procedures, Operative;Methods;Kirurški postopki, operativni;Metode;
URN:	URN:NBN:SI:doc-P6BAVXTX
Type (COBISS):	Scientific work
Pages:	str. 422-434
Volume:	Letn. 81
Issue:	št. 5
Chronology:	maj 2012
ID:	1725978