Daniel Košuta (Author), Borut Jug (Author), Zlatko Fras (Author)

Abstract

Coronary computed tomographic angiography (CCTA) is a promising technique for ruling out coronary artery disease (CAD) in patients with chest pain. We aimed to investigate the prognostic impact of nonobstructive CAD on CCTA. We retrospectively reviewed patients who underwent CCTA between 2010 and 2016 at our institution. We divided them into 3 groups: (1) patients with no CAD, (2) patients with nonobstructive CAD, and (3) patients with obstructive CAD. We investigated the incidence of the primary outcome (combination of death, nonfatal myocardial infarction, unstable angina, and late revascularization). A total of 989 patients were included: 540 patients had CAD, which was obstructive (≥50% stenosis) in 256 cases. During the follow-up period, 99 events occurred (32 [7%] in patients without CAD, 26 [9%] in patients with nonobstructive CAD, and 41 [16%] in patients with obstructive CAD; P < .001). The presence of nonobstructive and obstructive CAD was an independent predictor of events (HR: 2.33 [1.15-4.69], P < .001; and 4.02 [1.98-8.13], P = .019, respectively) compared with no CAD. Nonobstructive CAD on CCTA is associated with a 2-fold increase in risk of coronary events compared with patients with no CAD.

Keywords

koronarna arterijska bolezen;koronarna računalniška tomografija;angiografija;prognoza;

Data

Language: English
Year of publishing:
Typology: 1.01 - Original Scientific Article
Organization: UL MF - Faculty of Medicine
UDC: 616.1
COBISS: 56835075 Link will open in a new window
ISSN: 0003-3197
Views: 37
Downloads: 12
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Other data

Secondary language: Slovenian
Secondary keywords: koronarna arterijska bolezen;koronarna računalniška tomografija;angiografija;prognoza;
Type (COBISS): Article
Pages: str. 749-753
Volume: ǂVol. ǂ72
Issue: ǂiss. ǂ8
Chronology: 2021
DOI: 10.1177/0003319721999494
ID: 17908331