Matej Butala (Author), Anna Oslizlo (Author)

Abstract

As part of their survival strategy under harsh environmental conditions, endospore-forming bacteria can trigger a sporulation developmental program. Although the regulatory cascades that precisely control the transformation of vegetative bacteria into mother cells and resilient spores have been described in detail, less is known about how bacteriophages that prey on endospore-formers exploit sporulation. Herein, we argue that phages infecting these bacteria have evolved several specific molecular mechanisms, not yet known in other bacteria, that manifest from the phage-driven alliance to negative effects on the host. We anticipate that the relationships between phages and endospore-formers outlined here will inspire studies on phage ecology and evolution, and could facilitate important advances in the development of phage therapies against pathogenic spore-formers.

Keywords

ekologija mikroorganizmov;bakteriofagi;sporogene bakterije;

Data

Language: English
Year of publishing:
Typology: 1.02 - Review Article
Organization: UL BF - Biotechnical Faculty
UDC: 579.25/.26:578.347
COBISS: 135140099 Link will open in a new window
ISSN: 0966-842X
Views: 321
Downloads: 38
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Other data

Secondary language: Slovenian
Secondary keywords: ekologija mikroorganizmov;bakteriofagi;sporogene bakterije;
Type (COBISS): Article
Pages: str. 498-510
Volume: ǂVol. ǂ31
Issue: ǂno. ǂ5
Chronology: 2023
DOI: 10.1016/j.tim.2022.11.009
ID: 18873807