Fluorescent covalent organic frameworks

promising bioimaging materials

Chimatahalli Santhakumar Karthik (Author), Tina Škorjanc (Author), Dinesh Shetty (Author)

Abstract

Fluorescent covalent organic frameworks (COFs) have emerged as promising candidates for imaging living cells due to their unique properties and adjustable fluorescence. In this mini-review, we provide an overview of recent advancements in fluorescent COFs for bioimaging applications. We discuss the strategies used to design COFs with desirable properties such as high photostability, excellent biocompatibility, and pH sensitivity. Additionally, we explore the various ways in which fluorescent COFs are utilized in bioimaging, including cellular imaging, targeting specific organelles, and tracking biomolecules. We delve into their applications in sensing intracellular pH, reactive oxygen species (ROS), and specific biomarkers. Furthermore, we examine how functionalization techniques enhance the targeting and imaging capabilities of fluorescent COFs. Finally, we discuss the challenges and prospects in the field of fluorescent COFs for bioimaging in living cells, urging further research in this exciting area.

Keywords

covalent organic frameworks;fluorescent materials;imaging;bioimaging;biosensors;

Data

Language:	English
Year of publishing:	2024
Typology:	1.01 - Original Scientific Article
Organization:	UNG - University of Nova Gorica
UDC:	620.1/.2
COBISS:	187672835
ISSN:	2051-6355
Views:	196
Downloads:	3
Average score:	0 (0 votes)
Metadata:

Other data

Pages:	str. 1-18
Chronology:	2024
DOI:	10.1039/D3MH01698F
ID:	23073756