Marija Šantl-Letonja (Author), Mitja Letonja (Author), Jovana Nikolajević-Starčević (Author), Danijel Petrovič (Author)

Abstract

Namen: V raziskavi smo želeli ugotoviti prevalenco biokemičnih in kliničnih dejavnikov tveganja ter razširjenost ateroskleroze karotidnih arterij pri bolnikih s sladkorno boleznijo tipa 2 (SBT2). Metode: V prospektivno presečno študijo smo vključili 289 bolnikov s SBT2 in 157 zdravih preiskovancev. Anamnestične in klinične podatke smo zajeli z enotnim vprašalnikom. Vrednosti celokupnega holesterola, LDL in HDL holesterola, trigliceridov, glukoze, fibrinogena ter visokoobčutljivega C-reaktivnega proteina (CRP) smo določili s standardnimi biokemijskimi postopki. Aterosklerozo karotidnih arterij smo ocenili z ultrazvokom in opredelili debelino intime in medije, tip plakov ter seštevek plakov.

Keywords

diabetes mellitus;carotid atherosclerosis;markers of atherosclerosis;

Data

Language: English
Year of publishing:
Typology: 1.02 - Review Article
Organization: UM MF - Faculty of Medicine
UDC: 616.379-008.64:616-008.9
COBISS: 24153912 Link will open in a new window
ISSN: 1855-5640
Parent publication: Acta medico-biotechnica
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Other data

Secondary language: Slovenian
Secondary title: Ultrazvočni in klasični dejavniki tveganja karotidne ateroskleroze pri bolnikih s sladkorno boleznijo tipa 2
Secondary abstract: Purpose: We determined the prevalence of the clinical and biochemical risk factors as well as the extent of atherosclerosis in carotid arteries in patients with diabetes mellitus type 2(DMT2). Methods: A total of 289 subjects with DMT2 and 157 healthy subjects were enrolled in this prospective cross-sectional study. Leveles of total cholesterol, high-density lipoprotein-cholesterol (HDL-C), low-density lipoprotein-cholesterol (LDL-C), triglycerides, fasting, blood glucose, fribrinogen, and high-sensitivity C-reactive protein (hsCRP) were measured using standard biochemical methods. Carotid atherosclerosis was assessed by ultrasonography. Intima media thickness (IMT), plaque type and plaque score were also determined.
Secondary keywords: karotidna ateroskleroza;sladkorna bolezen;metabolni sindrom;
URN: URN:NBN:SI
Type (COBISS): Scientific work
Pages: str. 33-44
Volume: ǂVol. ǂ6
Issue: ǂ[no. ǂ1
Chronology: 2013
ID: 23412317