Ana Perpar (Author), Erik Brecelj (Author), Nada Rotovnik-Kozjek (Author), Franc Anderluh (Author), Irena Oblak (Author), Marija Skoblar Vidmar (Author), Vaneja Velenik (Author)

Abstract

Thrombotic events, arterial or venous in origin, still remain a source of substantial morbidity and mortality in cancer patients. The propensity for their development in oncology patients is partially a consequence of the disease itself and partially a result of our attempts to treat it. One of the rarest and deadliest thromboembolic complications is arterial mesenteric ischemia. The high mortality rate is caused by its rarity and by its non-specific clinical presentation, both of which make early diagnosis and treatment difficult. Hence, most diagnoses and treatments occur late in the course of the disease. The issue survivors of arterial mesenteric ischemia may face is short bowel syndrome, which has become a chronic condition after the introduction of parenteral nutrition at home. We present a 73-year-old rectal cancer patient who developed acute arterial mesenteric thrombosis at the beginning of the pre-operative radiochemotherapy. Almost the entire length of his small intestine, except for the proximal 50 cm of it, and the ascending colon had to be resected. After multiorgan failure his condition improved, and he was able to successfully complete radical treatment (preoperative radiotherapy and surgery) for the rectal carcinoma, despite developing short bowel syndrome (SBS) and being dependent upon home-based parenteral nutrition to fully cover his nutritional needs. Mesenteric ischemia and resultant short bowel syndrome are not absolute contraindications for radical oncological treatment since such patients can still achieve long-term remission.

Keywords

acute mesenteric ischemia;capecitabine;multiorgan failure;rectal cancer;short bowel syndrome;

Data

Language: English
Year of publishing:
Typology: 1.03 - Short Scientific Article
Organization: OI - Institute of Oncology
Publisher: Association of Radiology and Oncology
UDC: 616.351-006-005.4-08
COBISS: 281458176 Link will open in a new window
ISSN: 1318-2099
Views: 22
Downloads: 4
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Other data

Secondary language: Slovenian
Secondary keywords: rak (medicina);danka;rak danke;zdravljenje;ishemija mezenterija;sindrom kratkega črevesa;zapleti;
Pages: str. 181-184, VII
Volume: ǂVol. ǂ49
Issue: ǂno. ǂ2
Chronology: Jun. 2015
DOI: 10.2478/raon-2014-0024
ID: 23502153