ǂthe ǂinfluence of an alkyl substituent in 1,3-propanediamine chain and the metal counter cation on the structural properties of the complex
Bojana V. Pantović (Author), Darko P. Ašanin (Author), Franc Perdih (Author), Dušanka Radanović (Author), Iztok Turel (Author), Miloš I. Djuran (Author), Biljana Đ. Glišić (Author)

Abstract

The hexadentate 1,3-propanediamine-N,N,N’,N’-tetraacetate (1,3-pdta$^{4−}$) and (±)-1,3-pentanediamine-N,N,N’,N’-tetraacetate (1,3-pndta$^{4−}$) ligands were used for the synthesis of two new gallium(III) complexes, Na[Ga(1,3-pdta)]⋅3H$_2$O (1) and Ba[Ga(1,3-pndta)]$_2$⋅3H$_2$O (2). Complexes 1 and 2 were characterized by IR and NMR ($^1$H and $^{13}$C) spectroscopy and single crystal X-ray diffraction analysis. The obtained results have shown that both hexadentate 1,3-pdta$^{4−}$ and 1,3-pndta$^{4−}$ ligands are coordinated to gallium(III) ion through the two nitrogen and four carboxylate oxygen atoms. Both complexes show significant octahedral distortion since the mean angular deviation is nearly four degrees per angle. However, the octahedral distortion of complex 2 is lower than of 1, as indicated by the ΣΔ(O$_h$) values (48° and 49° versus 53°, respectively). The binding interactions of the complexes 1 and 2 with calf thymus DNA (ct-DNA) and bovine serum albumin (BSA) were studied by fluorescence emission spectroscopy. Both complexes can bind to the serum albumin reversibly, while their affinity to ct-DNA is rather low.

Keywords

galijevi(III) kompleksi;diaminopolikarboksilatni ligandi;spektroskopija;rentgenska difrakcijska analiza;interakcije DNA/BSA;gallium(III) complexes;diaminopolycarboxylate ligands;spectroscopy;X-ray diffraction analysis;DNA/BSA interactions;

Data

Language: English
Year of publishing:
Typology: 1.01 - Original Scientific Article
Organization: UL FKKT - Faculty of Chemistry and Chemical Technology
UDC: 546.681
COBISS: 196415491 Link will open in a new window
ISSN: 0277-5387
Views: 181
Downloads: 36
Average score: 0 (0 votes)
Metadata: JSON JSON-RDF JSON-LD TURTLE N-TRIPLES XML RDFA MICRODATA DC-XML DC-RDF RDF

Other data

Secondary language: Slovenian
Secondary keywords: galijevi(III) kompleksi;diaminopolikarboksilatni ligandi;spektroskopija;rentgenska difrakcijska analiza;interakcije DNA/BSA;
Type (COBISS): Article
Pages: str. 1-10
Issue: ǂVol. ǂ258, [article no.] 117045
Chronology: 1 Aug. 2024
DOI: 10.1016/j.poly.2024.117045
ID: 24230249
Recommended works:
, ǂthe ǂinfluence of an alkyl substituent in 1,3-propanediamine chain and the metal counter cation on the structural properties of the complex
, magistrsko delo
, diplomsko delo
, diplomsko delo Visokošolskega strokovnega študijskega programa I. stopnje Strojništvo
, diplomsko delo