Sinteza enaminonov na osnovi derivatov glikolne kisline in njihova uporaba v fotokataliziranih pretvorbah

diplomsko delo

Andrej Bogataj (Author), Uroš Grošelj (Mentor)

Abstract

Enaminoni so pomembne spojine za sintezo kompleksnejših organskih molekul, saj lahko zaradi svoje strukture sodelujejo v številnih reakcijah. Dve izmed teh sta aza-de Mayova reakcija in fotokataliziran prenos vodikovega atoma (HAT), s katerima se prek anuliranja lahko hitro pripravi ciklične spojine. V diplomskem delu sem iz Weinrebovega amida substituirane glikolne kisline sintetiziral keton in iz njega z N,N-dimetilformamid dimetil acetalom (DMFDMA) pripravil enaminon. Enaminon in nekaj drugih derivatov sem uporabil v aza-de Mayovi reakciji in fotokatalizirani HAT reakciji. Na enaminone sem izvedel tudi 1,4-adicijo Grignardovega reagenta.

Keywords

glikolna kislina;enaminoni;aza-de Mayova reakcija;1,4-adicija;prenos vodikovega atoma;HAT;diplomska dela;

Data

Language:	Slovenian
Year of publishing:	2025
Typology:	2.11 - Undergraduate Thesis
Organization:	UL FKKT - Faculty of Chemistry and Chemical Technology
Publisher:	[A. Bogataj]
UDC:	547.472.2:544.526.5(043.2)
COBISS:	247893763
Views:	142
Downloads:	54
Average score:	0 (0 votes)
Metadata:

Other data

Secondary language:	English
Secondary title:	Synthesis of enaminones based on glycolic acid derivatives and their use in photocatalyzed transformations
Secondary abstract:	Enaminones are important compounds for the synthesis of complex organic molecules, as their structure allows them to partake in numerous reactions. Two of these are aza-de Mayo reaction and photocatalyzed hydrogen atom transfer (HAT), which can be used to quickly obtain cyclic compounds via annulation. In my diploma thesis, I synthesized a ketone from Weinreb's amide of a substituted glycolic acid, and converted it into an enaminone using N,N-dimethylformamide dimethyl acetal (DMFDMA). I used the enaminone and several other derivatives in the aza-de Mayo reaction and in photocatalyzed HAT reaction. I also carried out the 1,4-addition of a Grignard reagent on enaminone reagents.
Secondary keywords:	enaminones;aza-de Mayo reaction;HAT;1,4-addition;Organska sinteza (kemija);Fotokataliza;Univerzitetna in visokošolska dela;
Type (COBISS):	Bachelor thesis/paper
Study programme:	1000373
Thesis comment:	Univ. v Ljubljani, Fak. za kemijo in kemijsko tehnologijo, UNI Kemija
Pages:	1 spletni vir (1 datoteka PDF (33 str.))
ID:	27261814