Sistem za ocenjevanje poškodb DNK

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Language:	Slovenian
Year of publishing:	2013
Source:	Ljubljana
Typology:	2.11 - Undergraduate Thesis
Organization:	UL FRI - Faculty of Computer and Information Science
Publisher:	[J. Janežič]
UDC:	004.42:577.21(043.2)
COBISS:	10233684
Views:	1921
Downloads:	282
Average score:	0 (0 votes)
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Secondary language:	English
Secondary title:	A system for evaluating the Dna damage
Secondary abstract:	The thesis describes the development and implementation of the system for the analysis of the comet assay. The first part describes the comet assay. It is a fast and simple process that enables the quantification of the damage of DNA molecules. We present the parameters needed for a precise analy¬sis of the comet assay. The system requirements are presented along with the currently available tools for comet assay analysis. Then we describe the technologies used during the development of the system. The programming language C# is used and the user interface was implemented with the WPF graphical subsystem. Chapter four presents the user interface and the main features of the developed system. The main focus of development was a sim¬ple user interface that enables a quick and precise analysis of the comet assay. The system supports the use of all major image formats. It supports simple manual marking as well as automated detection of the comets. The parame¬ters used in the analysis are chosen by the user and the produced results can be exported into an image or a spreadsheet. The possible improvements of the developed system are presented in the conclusion.
Secondary keywords:	deoxyribonucleic acid;damage;comet assay;computer programming;computer science;diploma;
File type:	application/pdf
Type (COBISS):	Undergraduate thesis
Thesis comment:	Univ. v Ljubljani, Fak. za računalništvo in informatiko
Pages:	34 str.
Type (ePrints):	thesis
Title (ePrints):	A system for evaluating the Dna damage
Abstract (ePrints):	Diplomsko delo obsega razvoj in implementacijo programa za ocenjevanje poškodb DNK na podlagi kometnega testa. V prvem delu je opisan kometni test in njegov potek. Gre za postopek, pri katerem je na hiter in enostaven način mogoča kvantifikacija poškodb molekule DNK. Predstavljeni so para¬metri, potrebni za natančno analizo kometnega testa. Določene so zahteve za program in predstavljena trenutno dostopna orodja za analizo. Sledi opis tehnologij uporabljenih pri razvoju programa. Uporabili smo programski je¬zik C#, uporabniški vmesnik pa smo implementirali s pomočjo grafičnega podsistema WPF. V četrtem poglavju je predstavljen razvit program, njegov uporabniški vmesnik in glavne funkcije. Pri razvoju smo se osredotočili pred¬vsem na preprost in pregleden uporabniški vmesnik, ki omogoča hitro in na¬tančno analizo kometov. Program podpira uporabo vseh najbolj razširjenih formatov slikovnih datotek. Omogoča enostavno ročno in avtomatizirano označevanje kometov, izbiro parametrov za analizo in izvoz pridobljenih podatkov v slikovnem formatu ali tabeli. V zaključku so opisani predlogi za nadaljnje izboljšave programa.
Abstract (ePrints, secondary language):	The thesis describes the development and implementation of the system for the analysis of the comet assay. The first part describes the comet assay. It is a fast and simple process that enables the quantification of the damage of DNA molecules. We present the parameters needed for a precise analy¬sis of the comet assay. The system requirements are presented along with the currently available tools for comet assay analysis. Then we describe the technologies used during the development of the system. The programming language C# is used and the user interface was implemented with the WPF graphical subsystem. Chapter four presents the user interface and the main features of the developed system. The main focus of development was a sim¬ple user interface that enables a quick and precise analysis of the comet assay. The system supports the use of all major image formats. It supports simple manual marking as well as automated detection of the comets. The parame¬ters used in the analysis are chosen by the user and the produced results can be exported into an image or a spreadsheet. The possible improvements of the developed system are presented in the conclusion.
ID:	8310350