diplomsko delo univerzitetnega študijskega programa
Mateja Arnuš (Author), Irena Ban (Mentor), Matjaž Kristl (Co-mentor)

Abstract

Namen diplomskega dela je bil sinteza magnetitnih (Fe3O4) oziroma maghemitnih (γ–Fe2O3) magnetnih nanodelcev s postopkom soobarjanja, sinteza nanodelcev silike po Stöberjevi metodi in poskus oblačenja teh delcev s prevleko iz zlata. Nanodelci zlata namreč zagotavljajo primerno površino, na katero se lahko pripenjajo različne zdravilne učinkovine za zdravljenje rakavih obolenj. Pri sintezah železovih oksidov smo spremljali vpliv vrste železovih soli na lastnosti nanodelcev. Pri nanašanju prevleke iz zlata smo zasledovali uporabo različnih reducentov, čas redukcije in količino dodanega HAuCl4. Za kvalitativno karakterizacijo sintetiziranih produktov in prevleke smo uporabili rentgensko praškovno difrakcijo (XRD). S pomočjo dinamičnega sipanja laserske svetlobe (DLS) smo opazovali spreminjanje velikosti, polidisperznega indeksa in zeta potenciala nanodelcev silike. Vezavo posameznih funkcionalnih skupin na nanodelce železovih oksidov smo spremljali s Fourierjevo transformacijsko infrardečo spektroskopijo (FTIR). S transmisijsko elektronsko mikroskopijo (TEM) smo določili morfologijo sintetiziranih nanodelcev in opazovali uspešnost vezave prevleke iz zlata.

Keywords

metoda soobarjenja;magnetni nanodelci;silika;površinks obdelava;biomedicinske aplikacije;

Data

Language: Slovenian
Year of publishing:
Typology: 2.11 - Undergraduate Thesis
Organization: UM FKKT - Faculty of Chemistry and Chemical Engineering
Publisher: [M. Arnuš]
UDC: 544.226-027:620.3(043.2)
COBISS: 17487638 Link will open in a new window
Views: 2042
Downloads: 203
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Other data

Secondary language: English
Secondary title: SYNTHESIS AND CHARACTERIZATION OF IRON OXIDES NANOPARTICLES WITH GOLD COATING
Secondary abstract: The aim of the diploma thesis was the synthesis of magnetite (Fe3O4) and maghemite (γ–Fe2O3) nanoparticles by coprecipitation method, the synthesis of silica nanoparticles by Stöber method and an attempt to coat these nanoparticles with gold. Gold nanoparticles have an appropriate surface on which a variety of active components for the cancer treatments can be attached. In the syntheses of iron oxides, we observed the influence of the type of iron salts on the properties of the nanoparticles. During the process of gold coating we studied the use of different reductants, time of reduction and the amount of added HAuCl4. For a qualitative characterization of the synthesized gold coated nanoparticles we used X–ray diffraction (XRD). With the help of a dynamic laser light scattering (DLS) we monitored the changes of size, the polydispersion index and the zeta potential of silica nanoparticles. The binding of specific functional groups on the nanoparticles of iron oxides was observed with Fourier transform infrared spectroscopy (FTIR). The morphology of synthesized nanoparticles and the effectiveness of gold coating was determined with the transmission electron microscopy (TEM).
Secondary keywords: coprecipitation method;magnetic nanoparticles;silica;surface functionalization;biomedical applications;
URN: URN:SI:UM:
Type (COBISS): Undergraduate thesis
Thesis comment: Univ. v Mariboru, Fak. za kemijo in kemijsko tehnologijo
Pages: XIII, 70 f.
ID: 8727253