diplomsko delo univerzitetnega študijskega programa I. stopnje
Anja Palko (Author), Mojca Škerget (Mentor), Željko Knez (Co-mentor)

Abstract

Cilj diplomskega dela je bil raziskati vpliv reakcijskih parametrov (temperature, časa in koncentracije) na hidrolitsko sposobnost subkritične vode na osnovnem primeru diglikozida kvercetina – rutina. S pomočjo načrtovanja eksperimentov ter metodologije odzivnih površin smo skušali poiskati optimalne reakcijske parametre pri katerih dobimo najvišji izkoristek hidrolize rutina v kvercetin. Vsi eksperimenti so bili izvedeni v visoko-temperaturnem, visoko-tlačnem avtoklavu v inertni (dušikovi) atmosferi pri pogojih, ki smo jih v naprej določili z uporabo računalniškega programa Design-Expert 7.0. S pomočjo tekočinske kromatografije visoke ločljivosti smo določili koncentracijo kvercetina ter drugih produktov hidrotermične degradacije po obdelavi s subkritično vodo. Z uporabo metodologije odzivnih površin smo dobljene rezultate optimizirali in določili optimalne parametre, ki prispevajo k najvišjemu izkoristku kvercetina.

Keywords

subkritična voda;hidrotermična degradacija;rutin;hidroliza;centralno kompozitni načrt;metoda odzivnih površin;

Data

Language: Slovenian
Year of publishing:
Typology: 2.11 - Undergraduate Thesis
Organization: UM FKKT - Faculty of Chemistry and Chemical Engineering
Publisher: [A. Palko]
UDC: 66.094.941:577.164.3(043.2)
COBISS: 18214166 Link will open in a new window
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Other data

Secondary language: English
Secondary title: OPTIMIZATION OF RUTIN HYDROLYSIS USING RESPONSE SURFACE METHODOLOGY
Secondary abstract: The aim of this graduate thesis was to study the influence of reaction parameters (temperature, time and concentration) on the hydrolytic ability of subcritical water on the basic example of diglicoside quercetin – rutin. Highest yield of quercetin was based on experimental design and response surface methodology optimal reaction parameters at wich the highest yield of quercetin is obtained were determined. All experiments were performed in a high-temperature high-pressure autoclave using an inert (nitrogen) atmosphere at condition, which were predefined using Design-Expert 7.0 software. Yield of quercetin and other products of hydrothermal degradation in samples after treatment with subcritical water were determined using high-performance liquid chromatography. Obtained results were optimized using response surface methodology and the optimal parameters, which contributed to the highest yield of quercetin were determined.
Secondary keywords: subcritical water;hydrothermal degradation;rutin;hydrolysis;central composite design;response surface methodolgy;
URN: URN:SI:UM:
Type (COBISS): Bachelor thesis/paper
Thesis comment: Univ. v Mariboru, Fak. za kemijo in kemijsko tehnologijo
Pages: X, 34 str.
ID: 8730022