Zollinger-Ellisonov sindrom: prikaz primera

Mitja Krajnc (Author), Miro Čokolič (Author)

Abstract

Izhodišča. Zollinger-Ellisonov sindrom je izjemno redka bolezen, ki je posledica čezmernega in avtonomnega izločanja gastrina iz gastrinomskih celic. Za bolezen je značilna huda in na zdravljenje odporna oblika ulkusne bolezni prebavil, ki lahko ogroža življenje bolnika. Tumor je v večini primerov maligen. Prikazan je primer 44-letnega bolnika s to boleznijo. Zaključki. Predstavljamo načela sodobne obravnave bolnika s sumom na Zollinger-Ellisonov sindrom: klinično sliko, laboratorijsko diagnostiko in preiskave za zamejitev tumorja ter osnove zdravljenja. Tumor je bil pri našem bolniku patohistološko opredeljen kot karcinoid z manjšim deležem gastrinomskih celic.

Keywords

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Data

Language:	Slovenian
Year of publishing:	2006
Typology:	1.04 - Professional Article
Organization:	UM - University of Maribor
UDC:	616.37
COBISS:	2495807
ISSN:	1318-0347
Parent publication:	Zdravniški vestnik
Views:	1815
Downloads:	54
Average score:	0 (0 votes)
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Other data

Secondary language:	English
Secondary title:	Zollinger-Ellison syndrome: a case report
Secondary abstract:	Background. Zollinger-Ellison syndrome is the consequence of excessive and autonomous secretion of gastrin from gastrinoma cells. The disease is exceptionally rare and characterized by severe and treatment-resistant peptic disease that can become life-threatening for a patient. In most cases, gastrinoma is malignant. A case of 44-year patient is presented. Conclusions. We present clinical manifestations, laboratory diagnostic tests, modalities of tumor localization and forms of treatment that are clinically relevant in a patient, suspected of having this rare disease. Pathohistologically, our patient's tumor was identified as a carcinoid with minor gastrinoma fraction.
Secondary keywords:	Zollinger-Ellison Syndrome;diagnosis;therapy;Zollinger-Ellisonov sindrom;Diagnostika;Zdravljenje;Gastrinoma;Gastrinom;Diagnosis, Differential;Diferencialna diagnostika;
URN:	URN:NBN:SI
Type (COBISS):	Not categorized
Pages:	str. II-111 - II-115
Volume:	ǂLetn. ǂ75
Issue:	ǂsupl. ǂII
Chronology:	2006
ID:	9089332