Novejša spoznanja o etiologiji kronične vnetne črevesne bolezni

Abstract

V prispevku so prikazana novejša spoznanja o etiologiji kronične vnetne črevesne bolezni, ki ostaja nejasna, kljub intenzivnim raziskavam. Vloga sluzničnega imunskega sistema je v zadnjih letih nesporno dokazana v mehanizmukronične vnetne črevesne bolezni, čeprav efektorni mehanizmi bolezni,kot tudi ciljne celice še niso popolnoma prepoznani. Raziskave so v zadnjem desetletju usmerjene predvsem na imunologijo, genetiko in infektologijo. Kot možne povzročitelje navajajo številne mikrobe, med katerimi so najpogostejši Mycobacterium paratuberculosis, virus ošpic in Listeria monocytogenes. Vse te raziskave lahko bistveno vplivajo na diagnostiko in zdravljenje klasičnih oblik kroničnih vnetnih črevesnih bolezni in njihovih različic.

Keywords

kronična vnetna črevesna bolezen;etiologija;

Data

Language:	Slovenian
Year of publishing:	2000
Typology:	1.02 - Review Article
Organization:	UM FZV - Faculty of Health Sciences
Publisher:	Medicinski razgledi
UDC:	616.3
COBISS:	460964
ISSN:	0025-8121
Parent publication:	Medicinski razgledi
Views:	1123
Downloads:	24
Average score:	0 (0 votes)
Metadata:

Other data

Secondary language:	English
Secondary title:	Recent advances in the etiology of the chronic inflammatory bowel disease
Secondary abstract:	In the article recent advances in the etiology of inflammatory bowel disease, which remain unknown despite intensive research effort, are presented. The role of the mucosal immune system in the mechanismus of inflammatory bowel disease, have been proven although the effector mechanism as well as target cells have not been precisely identifed. In the past decade, research was directed particulary toward immunology , genetics and infectology. Numerous microbes are mentioned as possible agents, most frequently Mycobacterium paratuberculosis, measles virus and Listeria monocytogenes. All these studies may have a sifgnificant impact on diagnosis and treatment of classical forms of chronic intestinal diseases and their variants.
Secondary keywords:	Inflammatory Bowel Diseases;Kronična vnetna črevesna bolezen;
URN:	URN:NBN:SI
Type (COBISS):	Not categorized
Pages:	str. 159-167
Volume:	ǂLetn. ǂ39
Issue:	ǂšt. ǂ2
Chronology:	2000
ID:	9099894