Eozinofilija pri bolniku z ekstranodalnim limfomom T naravnih ubijalk - prikaz primera

Vlasta Petric (Author), Alenka Benkovič (Author), Ivana Kološa (Author), Mateja Horvat (Author), Anton Lopert (Author), Metka Volavšek (Author), Srečko Kovačič (Author)

Abstract

Izhodišča. Eozinofilija se lahko pojavi tudi pri ekstranodalnem limfomu T naravnih ubijalk (T/NU). Če je dolgotrajna, lahko vodi v okvaro srčne mišice. Bolniki in metode. Prikazujemo primer bolnika z eozinofilijo, ugotovljeno devet mesecev pred postavitvijo diagnoze ekstranodalnega limfoma T/NU grla. Bolnik je umrl zaradi srčne odpovedi 11 mesecev po prvih simptomih. Na obdukciji je bila ugotovljena fibroza endomiokarda kot posledica kronične eozinofilije. Zaključki. Eozinofilija pri ekstranodalnem limfomu T/NU še ni bila opisana, zato menimo, da gre za redek primer. Pri bolnikih z izrazito eozinofilijo je pomembno zgodnje odkrivanje okvare srca, ki je lahko asimptomatska.

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Data

Language:	Slovenian
Year of publishing:	2003
Typology:	1.04 - Professional Article
Organization:	UM - University of Maribor
UDC:	616.32
COBISS:	1208383
ISSN:	1318-0347
Parent publication:	Zdravniški vestnik
Views:	1046
Downloads:	32
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Other data

Secondary language:	English
Secondary title:	ǂA ǂcase of extranodal NK/T cell lymphoma presenting with eosinophilia
Secondary abstract:	Background. Eosinophilia can occur in extranodal NK/T cell lymphoma. Chronic hypereosinophilia from any cause is associated with endomyocardial fibrosis. Methods and material. This report includes on a patient with hypereosinophilia which was diagnosed and investigated nine months before the diagnosis of extranodal NK/T cell lymphoma (nasal type) of the larynx was confirmed by biopsy. He died with signs of heart failure 11 months after the first symptoms developed. Post mortem investigation revealed endomyocardial fibrosis as a result of chronic hypereosinophilia. Conclusions. To our knowledge eosinophilia has not previously been reported in extranodal NK/T cell lymphoma (nasal type). Therefore, this is considered to be a rare feature of the presented case. Investigation of the heart for potential silent complications of prolonged and severe eosinophilia has to be considered at an early stage.
Secondary keywords:	Eosinophilia;Eozinofilija;Endomyocardial fibrosis;Fibroza endomiokarda;Killer cells, natural;Celice ubijalke, naravne;Lymphoma, T-cell;Limfom, T-celice;
URN:	URN:NBN:SI
Type (COBISS):	Not categorized
Pages:	str. 271-273
Volume:	ǂLetn. ǂ72
Issue:	ǂšt. ǂ5
Chronology:	2003
ID:	9109117