Joachim Habel (Author), Michael R. Hansen (Author), Søren Kynde (Author), Nanna Larsen (Author), Søren Roi Midtgaard (Author), Grethe Vestergaard Jensen (Author), Julie Bomholt (Author), Anayo Ogbonna (Author), Kristoffer Almdal (Author), Alexander Schulz (Author), Claus Hélix-Nielsen (Author)

Abstract

In recent years, aquaporin biomimetic membranes (ABMs) for water separation have gained considerable interest. Although the first ABMs are commercially available, there are still many challenges associated with further ABM development. Here, we discuss the interplay of the main components of ABMs: aquaporin proteins (AQPs), block copolymers for AQP reconstitution, and polymer-based supporting structures. First, we briefly cover challenges and review recent developments in understanding the interplay between AQP and block copolymers. Second, we review some experimental characterization methods for investigating AQP incorporation including freeze-fracture transmission electron microscopy, fluorescence correlation spectroscopy, stopped-flow light scattering, and small-angle X-ray scattering. Third, we focus on recent efforts in embedding reconstituted AQPs in membrane designs that are based on conventional thin film interfacial polymerization techniques. Finally, we describe some new developments in interfacial polymerization using polyhedral oligomeric silsesquioxane cages for increasing the physical and chemical durability of thin film composite membranes.

Keywords

aquaporins;biomimetic membranes;block copolymers;proteopolymersomes;polyhedral oligomeric silsesquioxanes;polyamide layer;microfluidics;membrane proteins;protein-polymer-interactions;

Data

Language: English
Year of publishing:
Typology: 1.02 - Review Article
Organization: UM FKKT - Faculty of Chemistry and Chemical Engineering
UDC: 577:004.7
COBISS: 18909718 Link will open in a new window
ISSN: 2077-0375
Views: 1165
Downloads: 114
Average score: 0 (0 votes)
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Other data

Secondary language: Slovenian
Secondary keywords: akvaporini;biomimetične membrane;blok-kopolimeri;poliamidni sloj;mikrofluidika;membranske beljakovine;
URN: URN:SI:UM:
Type (COBISS): Scientific work
Pages: str. 307-351
Volume: ǂVol. ǂ5
Issue: ǂiss. ǂ3
Chronology: 2015
DOI: 10.3390/membranes5030307
ID: 9142715