Tanja Peric (Avtor), A. Comin (Avtor), M. Corazzin (Avtor), M. Montillo (Avtor), F. Canavese (Avtor), Marco Stebel (Avtor), A. Prandi (Avtor)

Povzetek

The aim of this study was to assess hair cortisol concentrations in New Zealand white rabbits (Oryctolagus cuniculus) that were subjected to relocation and surgery to evaluate HPA-axis activity; in addition, we used this marker of cortisol secretion to evaluate the allostatic load of animals undergoing surgery. After a period of acclimatisation, which lasted 40 days from their arrival at the enclosure, 19 rabbits were subjected to T1–T12 dorsal arthrodesis (RS), 19 were sham-operated (SS), and 19 were non-operated (CON). Hair samples were collected at the time of arrival (ST1) at the animal facility, and seven other sets of hair samples were collected at 40-day intervals from the same area of skin for a period of 240 days as re-shaved hair (anagen phase): immediately before surgery (ST2) and after the surgery (ST3, ST4, ST5, ST6, ST7, and ST8). The transition from the rabbitry to the animal breeding facility led to a significant increase in cortisol concentration (ST2) in all of the groups. At ST3, the RS group presented higher cortisol concentrations than those of the SS group and the CON group. At ST4, the experimental groups showed similar values that remained constant until ST8. The results show that the management of rabbits undergoing surgery should be evaluated very carefully, and hair cortisol concentrations may provide a means of avoiding the dangerous cumulative effects of additional stressors close to surgery.

Ključne besede

cortisol;HPA axis;hair;rabbits;surgery;

Podatki

Jezik: Angleški jezik
Leto izida:
Tipologija: 1.01 - Izvirni znanstveni članek
Organizacija: UNG - Univerza v Novi Gorici
UDK: 636.1/.9
COBISS: 5061115 Povezava se bo odprla v novem oknu
ISSN: 0962-7286
Št. ogledov: 3386
Št. prenosov: 0
Ocena: 0 (0 glasov)
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Ostali podatki

URN: URN:SI:UNG
Vrsta dela (COBISS): Delo ni kategorizirano
Strani: str. 13-20
Letnik: ǂVol. ǂ27
Zvezek: ǂno. ǂ1
Čas izdaje: 2018
DOI: 10.7120/09627286.27.1.013
ID: 10904423
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, ǂan ǂindicator of HPA activity in relation to environmental perception in New Zealand White rabbit