Predicting "Heart Age" using electrocardiography

Robyn L. Ball (Avtor), Alan H. Feiveson (Avtor), Todd T. Schlegel (Avtor), Vito Starc (Avtor), Alan R. Dabney (Avtor)

Povzetek

Knowledge of a patient's cardiac age, or "heart age", could prove useful to both patients and physicians for better encouraging lifestyle changes potentially beneficial for cardiovascular health. This may be particularly true for patients who exhibit symptoms but who test negative for cardiac pathology. We developed a statistical model, using a Bayesian approach, that predicts an individual's heart age based on his/her electrocardiogram (ECG). The model is tailored to healthy individuals, with no known risk factors, who are at least 20 years old and for whom a resting 5 min 12-lead ECG has been obtained. We evaluated the model using a database of ECGs from 776 such individuals. Secondarily, we also applied the model to other groups of individuals who had received 5-min ECGs, including 221 with risk factors for cardiac disease, 441 with overt cardiac disease diagnosed by clinical imaging tests, and a smaller group of highly endurance-trained athletes. Model-related heart age predictions in healthy non-athletes tended to center around body age, whereas about three-fourths of the subjects with risk factors and nearly all patients with proven heart diseases had higher predicted heart ages than true body ages. The model also predicted somewhat higher heart ages than body ages in a majority of highly endurance-trained athletes, potentially consistent with possible fibrotic or other anomalies recently noted in such individuals.

Ključne besede

cardiac age;statistical model;electrocardiography;

Podatki

Jezik:	Angleški jezik
Leto izida:	2014
Tipologija:	1.01 - Izvirni znanstveni članek
Organizacija:	UL MF - Medicinska fakulteta
UDK:	616.1
COBISS:	31208153
ISSN:	2075-4426
Št. ogledov:	339
Št. prenosov:	52
Ocena:	0 (0 glasov)
Metapodatki:

Ostali podatki

Sekundarni jezik:	Slovenski jezik
Sekundarne ključne besede:	starost srca;statistični model;elektokardiografija;
Vrsta dela (COBISS):	Članek v reviji
Strani:	str. 65-78
Letnik:	ǂVol. ǂ4
Zvezek:	ǂiss. ǂ1
Čas izdaje:	Mar. 2014
DOI:	10.3390/jpm4010065
ID:	13296260