Microfluidic technology for clinical applications of exosomes

Florina Silvia Iliescu (Avtor), Danilo Vrtačnik (Avtor), Pavel Neuzil (Avtor), Ciprian Iliescu (Avtor)

Povzetek

Exosomes, a type of nanovesicle, are distinct cellular entities specifically capable of carrying various cargos between cells. It has been hypothesized that exosomes, as an enriched source of biomolecules, may serve as biomarkers for various diseases. This review introduces general aspects of exosomes, presents the challenges in exosome research, discusses the potential of exosomes as biomarkers, and describes the contribution of microfluidic technology to enable their isolation and analysis for diagnostic and disease monitoring. Additionally, clinical applications of exosomes for diagnostic purposes are also summarized.

Ključne besede

mikrofluidika;eksosomi;klinične aplikacije;zunajcelični vezikli;rak;vnetje;microfluidics;exosomes;clinical applications;extracellular vesicles;cancer;inflammation;

Podatki

Jezik:	Angleški jezik
Leto izida:	2019
Tipologija:	1.02 - Pregledni znanstveni članek
Organizacija:	UL FE - Fakulteta za elektrotehniko
UDK:	616-006:621.38
COBISS:	12545876
ISSN:	2072-666X
Št. ogledov:	209
Št. prenosov:	64
Ocena:	0 (0 glasov)
Metapodatki:

Ostali podatki

Sekundarni jezik:	Slovenski jezik
Sekundarne ključne besede:	mikrofluidika;eksosomi;klinične aplikacije;zunajcelični vezikli;rak;vnetje;
Vrsta dela (COBISS):	Članek v reviji
Strani:	str. 1-29
Letnik:	ǂiss. ǂ6
Zvezek:	392
Čas izdaje:	2019
DOI:	10.3390/mi10060392
ID:	13715156