Janez Kosel (Avtor), Ion Gutierrez-Aguirre (Avtor), Nejc Rački (Avtor), Tanja Dreo (Avtor), Maja Ravnikar (Avtor), Matevž Dular (Avtor)

Povzetek

The aim of this study was to accurately quantify the impact of hydrodynamic cavitation on the infectivity of bacteriophage MS2, a norovirus surrogate, and to develop a small scale reactor for testing the effect of hydrodynamic cavitation on human enteric viruses, which cannot be easily prepared in large quantities. For this purpose, 3 mL scale and 1 L scale reactors were constructed and tested. Both devices were efficient in generating hydrodynamic cavitation and in reducing the infectivity of MS2 virus. Furthermore, they reached more than 4 logs reductions of viral infectivity, thus confirming the scalability of hydrodynamic cavitation for this particular application. As for the mechanism of page inactivation, we suspect that cavitation generated OH% radicals formed an advanced oxidation process, which could have damaged the host's recognition receptors located on the surface of the bacteriophage. Additional damage could arise from the high shear forces inside the cavity. Moreover, the effectiveness of the cavitation was higher for suspensions containing low initial viral titers that are in similar concentration to the ones found in real water samples. According to this, cavitation generators could prove to be a useful tool for treating virus-contaminated wastewaters in the future.

Ključne besede

MS2 bacteriophage;norovirus surrogate;hydrodynamic cavitation;Venturi type constriction;phage infectivity;

Podatki

Jezik: Angleški jezik
Leto izida:
Tipologija: 1.01 - Izvirni znanstveni članek
Organizacija: UL FS - Fakulteta za strojništvo
UDK: 578.2:532(045)
COBISS: 15600923 Povezava se bo odprla v novem oknu
ISSN: 0043-1354
Št. ogledov: 13
Št. prenosov: 2
Ocena: 0 (0 glasov)
Metapodatki: JSON JSON-RDF JSON-LD TURTLE N-TRIPLES XML RDFA MICRODATA DC-XML DC-RDF RDF

Ostali podatki

Sekundarni jezik: Slovenski jezik
Sekundarne ključne besede: kavitacija;MS2 bakteriofag;venturijeva cev;virusi;infektivnost;
Vrsta dela (COBISS): Članek v reviji
Konec prepovedi (OpenAIRE): 2019-08-08
Strani: str. 465-471
Zvezek: ǂVol. ǂ124
Čas izdaje: Nov. 2017
DOI: 10.1016/j.watres.2017.07.077
ID: 18275611