Mojca Jensterle Sever (Avtor), Sončka Jazbinšek (Avtor), Roman Bošnjak (Avtor), Mara Popović (Avtor), Lorna Zadravec-Zaletel (Avtor), Vesna Plesničar (Avtor), Barbara Faganel (Avtor), Primož Kotnik (Avtor)

Povzetek

Childhood and adult-onset craniopharyngioma is a rare embryogenic tumor of the sellar, suprasellar, and parasellar region. Survival rates are high; however, tumor location and treatment sequalae including endocrine deficits, visual impairment, metabolic complications, cognitive and psychosocial deficits can significantly impair patient%s quality of life. There is considerable controversy regarding the optimal management of craniopharyngiomas. Subtotal resection of the tumor followed by targeted irradiation to avoid further hypothalamic damage is currently indicated. Novel insights in the tumor%s molecular pathology present the possibility for targeted therapy possibly decreasing the rate and severity of treatment-associated morbidity. Conclusions. Craniopharyngioma should be seen as a chronic disease. To achieve optimal outcomes a multidisciplinary team of specialized neurosurgeons, neuro-radiologists, neuro-oncologists, pathologists and endocrinologists should be involved in the diagnosis, planning of the surgery, irradiation and long-term follow-up.

Ključne besede

craniopharyngioma;hypopituitarism;metabolic syndrome;

Podatki

Jezik: Angleški jezik
Leto izida:
Tipologija: 1.02 - Pregledni znanstveni članek
Organizacija: OI - Onkološki inštitut Ljubljana
Založnik: Association of Radiology and Oncology
UDK: 616-006
COBISS: 34550489 Povezava se bo odprla v novem oknu
ISSN: 1318-2099
Št. ogledov: 36
Št. prenosov: 20
Ocena: 0 (0 glasov)
Metapodatki: JSON JSON-RDF JSON-LD TURTLE N-TRIPLES XML RDFA MICRODATA DC-XML DC-RDF RDF

Ostali podatki

Sekundarni jezik: Slovenski jezik
Sekundarne ključne besede: kraniofaringiom;hipopituitarizem;presnovni sindrom;
Komentar vira: Soavtorji: Soncka Jazbinsek, Roman Bosnjak, Mara Popovic, Lorna Zadravec Zaletel, Tina Vipotnik Vesnaver, Barbara Faganel Kotnik, Primoz Kotnik;
Strani: str. 388-396, I
Letnik: ǂVol. ǂ53
Zvezek: ǂno. ǂ4
Čas izdaje: dec. 2019
DOI: 10.2478/raon-2019-0036
ID: 24493265