Giovanna Romano (Avtor), Mariana Almeida (Avtor), Ana Varela Coelho (Avtor), Adele Cutignano (Avtor), Luís Moreira Gonçalves (Avtor), Espen Hansen (Avtor), Denis Khnykin (Avtor), Tali Mass (Avtor), Andreja Ramšak (Avtor), Miguel Rocha S. (Avtor), Tiago Henriques da Silva (Avtor), Michela Sugni (Avtor), Loriano Ballarin (Avtor), Anne-Marie Geneviere (Avtor)

Povzetek

Aquatic invertebrates are a major source of biomaterials and bioactive natural products that can find applications as pharmaceutics, nutraceutics, cosmetics, antibiotics, antifouling products and biomaterials. Symbiotic microorganisms are often the real producers of many secondary metabolites initially isolated from marine invertebrates; however, a certain number of them are actually synthesized by the macro-organisms. In this review, we analysed the literature of the years 2010–2019 on natural products (bioactive molecules and biomaterials) from the main phyla of marine invertebrates explored so far, including sponges, cnidarians, molluscs, echinoderms and ascidians, and present relevant examples of natural products of interest to public and private stakeholders. We also describe omics tools that have been more relevant in identifying and understanding mechanisms and processes underlying the biosynthesis of secondary metabolites in marine invertebrates. Since there is increasing attention on finding new solutions for a sustainable large-scale supply of bioactive compounds, we propose that a possible improvement in the biodiscovery pipeline might also come from the study and utilization of aquatic invertebrate stem cells.

Ključne besede

marine natural products;marine biomaterials;marine invertebrates;bioactivity;stem cells;

Podatki

Jezik: Angleški jezik
Leto izida:
Tipologija: 1.02 - Pregledni znanstveni članek
Organizacija: NIB - Nacionalni inštitut za biologijo
UDK: 556:557
COBISS: 103233539 Povezava se bo odprla v novem oknu
ISSN: 1660-3397
Št. ogledov: 30
Št. prenosov: 17
Ocena: 0 (0 glasov)
Metapodatki: JSON JSON-RDF JSON-LD TURTLE N-TRIPLES XML RDFA MICRODATA DC-XML DC-RDF RDF

Ostali podatki

Sekundarni jezik: Slovenski jezik
Sekundarne ključne besede: morske naravne spojine;morski biomateriali;morski nevretenčarji;bioaktivnost;matične celice;
Komentar vira: Nasl. z nasl. zaslona; Članek št. 219; Soavtorji: Mariana Almeida, Ana Varela Coelho,Adele Cutignano, Luis G Gonçalves, Espen Hansen, Denis Khnykin, Tali Mass, Andreja Ramšak, Miguel S. Rocha,Tiago H. Silva, Michela Sugni, Loriano Ballarin, Anne-Marie Genevière; Opis vira z dne 4. 4. 2022;
Strani: str. 1-45
Letnik: ǂVol. ǂ20
Zvezek: ǂiss. ǂ4
Čas izdaje: 2022
DOI: 10.3390/md20040219
ID: 24669919