Peter Perdih (Avtor), Sašo Čebašek (Avtor), Alenka Možir (Avtor), Ema Žagar (Avtor)

Povzetek

Carboxyl functional groups of poly(L-glutamic acid) (PGlu) were modified with a D-(+)-glucosamine (GlcN) by amidation using 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4- methylmorpholinium chloride (DMTMM) as a coupling reagent. The coupling reaction was performed in aqueous medium without protection of hydroxyl functional groups of D-(+)-glucosamine. Poly(L-glutamic acid) and GlcN functionalized polyglutamates (P(Glu-GlcN)) were thoroughly characterized by 1D and 2D NMR spectroscopy and SEC-MALS to gain detailed information on their structure, composition and molar mass characteristics. The results reveal successful functionalization with GlcN through the amide bond and also to a minor extent through ester bond formation in position 1 of GlcN. In addition, a ratio between the α- and β-form of glucosamine substituent coupled to polyglutamate repeating units as well as the content of residual dimethoxy triazinyl active ester moiety in the samples were evaluated.

Ključne besede

materiali;polimerizacija;struktura snovi;

Podatki

Jezik: Angleški jezik
Leto izida:
Tipologija: 1.01 - Izvirni znanstveni članek
Organizacija: KI - Kemijski inštitut
UDK: 620.1/.2
COBISS: 5609754 Povezava se bo odprla v novem oknu
ISSN: 1420-3049
Št. ogledov: 3867
Št. prenosov: 719
Ocena: 0 (0 glasov)
Metapodatki: JSON JSON-RDF JSON-LD TURTLE N-TRIPLES XML RDFA MICRODATA DC-XML DC-RDF RDF

Ostali podatki

Sekundarne ključne besede: materiali;polimerizacija;struktura snovi;
Vrsta dela (COBISS): Članek v reviji
Komentar vira: Sodelavci: Sašo Čebašek, Alenka Možir and Ema Žagar; Nasl. z nasl. zaslona; Opis vira z dne 1. 12. 2014;
Strani: str. 19751-19768
Letnik: ǂVol. ǂ19
Zvezek: ǂiss. ǂ12
Čas izdaje: Dec. 2014
DOI: 10.3390/molecules191219751
ID: 9145162