Povzetek

Genetic competence for the uptake and integration of extracellular DNA is a key process in horizontal gene transfer (HGT), one of the most powerful forces driving the evolution of bacteria. In several species, development of genetic competence is coupled with cell lysis. Using Bacillus subtilis as a model bacterium, we studied the role of surfactin, a powerful biosurfactant and antimicrobial lipopeptide, in genetic transformation. We showed that surfactin itself promotes cell lysis and DNA release, thereby promoting HGT. These results, therefore, provide evidence for a fundamental mechanism involved in HGT and significantly increase our understanding of the spreading of antibiotic resistance genes and diversification of microbial communities in the environment.

Ključne besede

Bacillus subtilis;zaznavanje kvoruma;horizontalni prenos genov;surfaktin;

Podatki

Jezik: Angleški jezik
Leto izida:
Tipologija: 1.01 - Izvirni znanstveni članek
Organizacija: UL BF - Biotehniška fakulteta
UDK: 579.22/.26:579.852.11
COBISS: 58756355 Povezava se bo odprla v novem oknu
ISSN: 1664-302X
Št. ogledov: 404
Št. prenosov: 112
Ocena: 0 (0 glasov)
Metapodatki: JSON JSON-RDF JSON-LD TURTLE N-TRIPLES XML RDFA MICRODATA DC-XML DC-RDF RDF

Ostali podatki

Sekundarni jezik: Slovenski jezik
Sekundarne ključne besede: Bacillus subtilis;zaznavanje kvoruma;horizontalni prenos genov;surfaktin;
Vrsta dela (COBISS): Članek v reviji
Strani: str. 1-8, article 657407
Zvezek: ǂVol. ǂ12
Čas izdaje: May 2021
DOI: 10.3389/fmicb.2021.657407
ID: 14129042
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