Katja Gorenc (Author), Tomaž Accetto (Author), Gorazd Avguštin (Author)

Abstract

Bioinformatic evidence of the presence of a large conjugative transposon in ruminal bacterium Prevotella bryantii B[sub]14[sup]T is presented. The described transposon appears to be related to another large conjugative transposon CTnBST, described in Bacteroides uniformis WH207 and to the conjugative transposon CTn3-Bf, which was observed in the genome of Bacteroides fragilis strain YCH46. All three transposons share tra gene regions with high amino acid identity and clearly conserved gene order. Additionally, a second conserved region consisting of hypothetical genes was discovered in all three transposons and named the GG region. This region served as a specific sequence signature and made possible the discovery of several other apparently related hypothetical conjugative transposons in bacteria from the genus Bacteroides. A cluster of genes involved in sugar utilization and metabolism was discovered within the hypothetical CTnB[sub]14, to a certain extent resembling the polysaccharide utilization loci which were described recently in some Bacteroides strains. This is the first firm report on the presence of a large mobile genetic element in any strain from the genus Prevotella.

Keywords

mikrobiologija;Bacteroides;Prevotella;molekularna genetika;genom;bioinformatika;

Data

Language: English
Year of publishing:
Typology: 1.01 - Original Scientific Article
Organization: UL BF - Biotechnical Faculty
UDC: 579:575
COBISS: 3042440 Link will open in a new window
ISSN: 0015-5632
Views: 1147
Downloads: 254
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Other data

Secondary language: English
Type (COBISS): Not categorized
Pages: str. 285-290
Volume: ǂVol. ǂ57
Issue: ǂno. ǂ4
Chronology: 2012
DOI: 10.1007/s12223-012-0126-5
ID: 1033802