Boštjan Murovec (Avtor), James M. Tiedje (Avtor), Blaž Stres (Avtor)

Povzetek

The exponential growth of available DNA sequences and the increased interoperability of biological information is triggering intergoivernmental efforts aimed at increasing the access, dissemination, and analysis of sequence data. Achieving the efficient storage and processing of DNA material is an important goal that parallels well with the foreseen coding standardization on the horizon. This paper proposes novel coding approaches, for both the dissemination and processing of sequences, where the speed of the DNA processing is shown to be boosted by exploring more than the normally utilized eight bits for encoding a single nucleotide. Further gains are achived by encoding the nucleotides together with their trailing alignament information as a single 64-bit data structure. the paper also proposes a slight modification to the established FASTA scheme in order to improve on its representation of alignament information. The significance of the proposition is confirmed by the encouraging results from empirical tests.

Ključne besede

molekularna genetika;DNK;sekvence;bioinformatika;

Podatki

Jezik: Angleški jezik
Leto izida:
Tipologija: 1.01 - Izvirni znanstveni članek
Organizacija: UL BF - Biotehniška fakulteta
UDK: 575
COBISS: 2625416 Povezava se bo odprla v novem oknu
ISSN: 0169-2607
Št. ogledov: 1138
Št. prenosov: 213
Ocena: 0 (0 glasov)
Metapodatki: JSON JSON-RDF JSON-LD TURTLE N-TRIPLES XML RDFA MICRODATA DC-XML DC-RDF RDF

Ostali podatki

Sekundarni jezik: Neznan jezik
Vrsta dela (COBISS): Delo ni kategorizirano
Strani: str. 175-190
Letnik: ǂVol. ǂ100
Zvezek: ǂno. ǂ2
Čas izdaje: 2010
DOI: 10.1016/j.cmpb.2010.03.014
ID: 1033714