ǂan ǂin vitro study of laser capsulotomy
Gregor Hawlina (Author), Brigita Drnovšek-Olup (Author), Janez Možina (Author), Peter Gregorčič (Author)

Abstract

A Nd:YAG laser photodisruption is a well-established tool for intraocular surgery, such as treatment of posterior capsule opacification that affects the visual function. During the intraocular procedure, called laser capsulotomy, the excitation pulse is focused several times just behind the posterior capsule and intraocular lens to create the central opening in the opacified capsule. We built an in vitro experiment to (1) clarify the influence of the distance between the intraocular lens and the posterior capsule on the total pulse energy required for the capsulotomy, and (2) investigate the main mechanisms responsible for the posterior capsule opening. In our in vitro model, different distances between the solid boundary (imitating an intraocular lens) and the membrane (imitating the posterior capsule) simulate different types of posterior capsule opacification. Our results show that procedure efficiency decreases by decreasing distance between the lens and the capsule. We also explain that for smaller distances between the pulse focus and the membrane, plasma and shock wave are responsible for the capsule disruption. Here, a risk of collateral damage significantly increases. On contrary, the membrane and the bubble jet disrupt the membrane, when pulse focus is moved away and the risk of intraocular lens damage decreases. However, the membrane disruption is not very effective, if it is placed near the solid boundary that inhibits the membrane jet.

Keywords

photodisruption laser;capsulotomy;cavitation bubble;

Data

Language: English
Year of publishing:
Typology: 1.01 - Original Scientific Article
Organization: UL FS - Faculty of Mechanical Engineering
UDC: 532.528(045)
COBISS: 14475803 Link will open in a new window
ISSN: 0947-8396
Views: 558
Downloads: 228
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Other data

Secondary language: Slovenian
Secondary keywords: fotodisrupcija;laserska kapsulotomija;kavitacijski mehurček;
Type (COBISS): Article
Pages: str. 1-7
Volume: ǂVol. ǂ122
Issue: ǂiss. ǂ2
Chronology: Feb. 2016
DOI: 10.1007/s00339-016-9648-z
ID: 10991285