Microbubble dynamics and jetting near tissue-phantom biointerfaces

Jaka Mur (Avtor), Vid Agrež (Avtor), Jaka Petelin (Avtor), Rok Petkovšek (Avtor)

Povzetek

Precise excitation of cavitation is a promising mechanism for microsurgery procedures and targeted drug delivery enhancement. The underlying phenomenon of interest, jetting behaviour of oscillating cavitation bubbles, occurs due to near-surface interactions between the boundary, liquid, and bubble. Within this study we measured boundary effects on the cavitation bubble dynamics and morphology, with an emphasis on observation and measurement of jetting behaviour near tissue-phantom biointerfaces. An important mechanism of boundary poration has been observed using time-resolved optical microscopy and explained for different tissue-phantom surface densities and Young’s modulus. Below a critical distance to the boundary, around γ = 1.0, the resulting jets penetrated the tissue-phantom, resulting in highly localized few micrometer diameter jets.

Ključne besede

cavitation bubbles;laser breakdown;tissue phantom;sonoporation;

Podatki

Jezik:	Angleški jezik
Leto izida:	2022
Tipologija:	1.01 - Izvirni znanstveni članek
Organizacija:	UL FS - Fakulteta za strojništvo
UDK:	532.528
COBISS:	97105923
ISSN:	2156-7085
Št. ogledov:	1292
Št. prenosov:	251
Ocena:	0 (0 glasov)
Metapodatki:

Ostali podatki

Sekundarni jezik:	Slovenski jezik
Sekundarne ključne besede:	kavitacijski mehurčki;laserski preboj;tkivni fantom;sonoporacija;
Vrsta dela (COBISS):	Članek v reviji
Strani:	str. 1061-1069
Letnik:	ǂVol. ǂ13
Zvezek:	ǂiss. ǂ2
Čas izdaje:	Feb. 2022
DOI:	10.1364/BOE.449814
ID:	14519276