diplomsko delo
Alen Fuks (Author), Polona Jamnik (Mentor), Polona Jamnik (Thesis defence commission member), Damjana Drobne (Thesis defence commission member), Jana Murovec (Thesis defence commission member)

Abstract

Diplomsko delo obsega predstavitev rezultatov določenih raziskav staranja na kvasovki kot modelnem organizmu. Zaradi vse večjega deleža starega prebivalstva, postaja staranje tema, ki se vedno bolj raziskuje z namenom kakovostnejšega in daljšega življenja. Na staranje lahko vplivamo z genetskim spreminjanjem, kot je utišanje ali delecija genov, tretiranjem s kemijskimi spojinami ter s spremembo prehrane, kjer vsi načini vplivajo na poti, ki zaznavajo dostopnost hranil. V prvem delu diplomskega dela je predstavljeno, zakaj je kvasovka lahko primerni model za študij procesov staranja, nato sta razložena replikativno (RLS) in kronološko staranje (CLS). Za tem sledi razlaga procesov, ki se dogajajo preko RLS in CLS v odvisnosti od aktiviranja/deaktiviranja poti, ki zaznavajo dostopnost hranil.

Keywords

staranje;poti zaznavanja hranil;biotehnologija;RLS;CLS;

Data

Language: Slovenian
Year of publishing:
Typology: 2.11 - Undergraduate Thesis
Organization: UL BF - Biotechnical Faculty
Publisher: [A. Fuks]
UDC: 601.4:582.282.23:57.017.6(043.2)
COBISS: 9363321 Link will open in a new window
Views: 626
Downloads: 113
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Other data

Secondary language: English
Secondary title: Yeast Saccharomyces cerevisiae as a model organism for the study of aging processes
Secondary abstract: This thesis consists of presenting the results of certain studies of yeast aging as a model organism. Due to the increasing share of the old population, aging is becoming a topic, which is being increasingly explored for the purpose of a better and longer life. Aging can be influenced by genetic modifications, such as shutting off genes or gene deletion, treatment with chemical compounds and with a change in diet, where all modes affect pathways, that sense nutrient availability. The first part of the thesis presents why yeast can be a suitable model for the study of aging processes and then replicative (RLS) and chronological (CLS) aging are explained. This is followed by an explanation of the processes that occur through RLS and CLS, depending on the activaton/deactivation of pathways that detect nutrient availability.
Secondary keywords: aging;nutrient detection pathways;biotechnology;
Type (COBISS): Bachelor thesis/paper
Study programme: 0
Embargo end date (OpenAIRE): 1970-01-01
Thesis comment: Univ. v Ljubljani, Biotehniška fak., Študij biotehnologije
Pages: VI, 20 str.
ID: 11223591